Arash Khojasteh1, Hossein Behnia, Navid Naghdi, Mohammad Esmaeelinejad, Zahra Alikhassy, Mark Stevens. 1. Assistant Professor of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Head, Division of Basic Sciences, Dental Research Center, Tehran, Iran. Electronic address: arashkhojasteh@yahoo.com.
Abstract
OBJECTIVE: The application and subsequent investigations in the use of varied osteogenic growth factors in bone regeneration procedures have grown dramatically over the past several years. Owing to this rapid gain in popularity and documentation, a review was undertaken to evaluate the in vivo effects of growth factors on bone regeneration. STUDY DESIGN: Using related key words, electronic databases (Medline, Embase, and Cochrane) were searched for articles published from 1999 to April 2010 to find growth factor application in bone regeneration in human or animal models. RESULTS: A total of 63 articles were matched with the inclusion criteria of this study. Bone morphogenetic protein 2 (BMP-2) was the most studied growth factor. Carriers for the delivery, experimental sites, and methods of evaluation were different, and therefore articles did not come to a general agreement. CONCLUSIONS: Within the limitations of this review, BMP-2 may be an appropriate growth factor for osteogenesis.
OBJECTIVE: The application and subsequent investigations in the use of varied osteogenic growth factors in bone regeneration procedures have grown dramatically over the past several years. Owing to this rapid gain in popularity and documentation, a review was undertaken to evaluate the in vivo effects of growth factors on bone regeneration. STUDY DESIGN: Using related key words, electronic databases (Medline, Embase, and Cochrane) were searched for articles published from 1999 to April 2010 to find growth factor application in bone regeneration in human or animal models. RESULTS: A total of 63 articles were matched with the inclusion criteria of this study. Bone morphogenetic protein 2 (BMP-2) was the most studied growth factor. Carriers for the delivery, experimental sites, and methods of evaluation were different, and therefore articles did not come to a general agreement. CONCLUSIONS: Within the limitations of this review, BMP-2 may be an appropriate growth factor for osteogenesis.
Authors: Anja Klein; Andreas Baranowski; Ulrike Ritz; Christiane Mack; Hermann Götz; Eva Langendorf; Bilal Al-Nawas; Philipp Drees; Pol M Rommens; Alexander Hofmann Journal: Eur J Trauma Emerg Surg Date: 2019-05-28 Impact factor: 3.693
Authors: A Khojasteh; S Hosseinpour; M M Dehghan; F Mashhadiabbas; M Rezai Rad; S Ansari; S Farzad Mohajeri; H H Zadeh Journal: Biomed Res Int Date: 2018-02-28 Impact factor: 3.411