| Literature DB >> 22900546 |
Takeo Sakai1, Satoshi Ito, Hiroki Furuta, Yuki Kawahara, Yuji Mori.
Abstract
An equatorial attack of TMS-diazomethane was determined to be the first step of the BF(3)-promoted ring expansion reaction of six-membered ketones using TMS-diazomethane. The migration reaction occurred in a conformation in which the carbonyl oxygen and the TMS group were antiperiplanar to predominantly afford trans-seven-membered ketones.Entities:
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Year: 2012 PMID： 22900546 DOI： 10.1021/ol302032w
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005