Literature DB >> 22900467

Local drug delivery to the bone by drug-releasing implants: perspectives of nano-engineered titania nanotube arrays.

Karan Gulati1, Moom Sinn Aw, David Findlay, Dusan Losic.   

Abstract

Titania nanotube (TNT) arrays fabricated by electrochemical anodization of titanium are currently one of the most attractive nanomaterials due to their remarkable properties. In this review, we highlight recent research activities that are focused on the application of the TNT arrays for local drug delivery, specifically for addressing problems associated with orthopedic implants. The advantages of drug-releasing implants based on TNT arrays for local delivery of therapeutics in bone related to these challenging problems including inflammation, infection and osseointegration are discussed. An overview of recent research to advance the drug-releasing performance of TNT arrays and the potential of their future applications and development are presented.

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Year:  2012        PMID： 22900467     DOI： 10.4155/tde.12.66

Source DB:  PubMed          Journal:  Ther Deliv        ISSN： 2041-5990


  14 in total

1.  (Bio)manufactured Solutions for Treatment of Bone Defects with Emphasis on US-FDA Regulatory Science Perspective.

Authors:  Pejman Ghelich; Mehdi Kazemzadeh-Narbat; Alireza Hassani Najafabadi; Mohamadmahdi Samandari; Adnan Memic; Ali Tamayol
Journal:  Adv Nanobiomed Res       Date:  2022-01-05

2.  Antibacterial Effects and Biocompatibility of Titania Nanotubes with Octenidine Dihydrochloride/Poly(lactic-co-glycolic acid).

Authors:  Zhiqiang Xu; Yingzhen Lai; Dong Wu; Wenxiu Huang; Sijia Huang; Lin Zhou; Jiang Chen
Journal:  Biomed Res Int       Date:  2015-05-19       Impact factor: 3.411

3.  Improved antibacterial activity and biocompatibility on vancomycin-loaded TiO2 nanotubes: in vivo and in vitro studies.

Authors:  Hangzhou Zhang; Yu Sun; Ang Tian; Xiang Xin Xue; Lin Wang; Ali Alquhali; Xizhuang Bai
Journal:  Int J Nanomedicine       Date:  2013-11-08

4.  Electrospun vancomycin-loaded coating on titanium implants for the prevention of implant-associated infections.

Authors:  Li Zhang; Junwei Yan; Zhaowei Yin; Cheng Tang; Yang Guo; Dong Li; Bo Wei; Yan Xu; Qiangrong Gu; Liming Wang
Journal:  Int J Nanomedicine       Date:  2014-06-23

Review 5.  TiO2 nanotube platforms for smart drug delivery: a review.

Authors:  Qun Wang; Jian-Ying Huang; Hua-Qiong Li; Zhong Chen; Allan Zi-Jian Zhao; Yi Wang; Ke-Qin Zhang; Hong-Tao Sun; Salem S Al-Deyab; Yue-Kun Lai
Journal:  Int J Nanomedicine       Date:  2016-09-21

6.  Inhibited Bacterial Adhesion and Biofilm Formation on Quaternized Chitosan-Loaded Titania Nanotubes with Various Diameters.

Authors:  Wen-Tao Lin; Yi-Yuan Zhang; Hong-Lue Tan; Hai-Yong Ao; Zhao-Ling Duan; Guo He; Ting-Ting Tang
Journal:  Materials (Basel)       Date:  2016-03-03       Impact factor: 3.623

7.  Controlled and sustained drug release performance of calcium sulfate cement porous TiO2 microsphere composites.

Authors:  Wei Luo; Zhen Geng; Zhaoyang Li; Shuilin Wu; Zhenduo Cui; Shengli Zhu; Yanqin Liang; Xianjin Yang
Journal:  Int J Nanomedicine       Date:  2018-11-14

Review 8.  Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches.

Authors:  Rebecca Rothe; Sandra Hauser; Christin Neuber; Markus Laube; Sabine Schulze; Stefan Rammelt; Jens Pietzsch
Journal:  Pharmaceutics       Date:  2020-05-06       Impact factor: 6.321

9.  Application of quality by design for 3D printed bone prostheses and scaffolds.

Authors:  Daniel Martinez-Marquez; Ali Mirnajafizadeh; Christopher P Carty; Rodney A Stewart
Journal:  PLoS One       Date:  2018-04-12       Impact factor: 3.240

Review 10.  The paradigm shift for drug delivery systems for oral and maxillofacial implants.

Authors:  Rafal Pokrowiecki
Journal:  Drug Deliv       Date:  2018-11       Impact factor: 6.419
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