[Ischemic occlusion of the central retinal vein and protein C deficiency].

We present a case of a 52-year-old woman suffering from an ischemic central retinal vein thrombosis with neovascular glaucoma of her left eye. Protein C activity was found to be reduced (32%). This supports the hypothesis that protein C may play a role in the pathogenesis of ocular vaso-occlusive disease, as protein C is an important inhibitor of hemostasis. Thus, we suggest to measure protein C in patients with preceding thromboembolic diseases or assumed disorders of coagulation.