| Literature DB >> 22898619 |
M G Alvarez1, C Vigliano, B Lococo, M Petti, G Bertocchi, R Viotti.
Abstract
In 12-18% of adult patients, treatment with benznidazole for chronic Chagas disease has to be discontinued because of side-effects. We identified and analysed a cohort of 81 adult patients with three positive tests for Trypanosoma cruzi infection and serological monitoring following incomplete treatment with benznidazole for a median of 10 days. Twenty percent of these patients (16/81) met the criteria of cure, showing that the optimal schedule of benznidazole administration remains to be determined.Entities:
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Year: 2012 PMID： 22898619 DOI： 10.1016/j.trstmh.2012.07.010
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184