Literature DB >> 22898490

The antimalarial pipeline--an update.

Florian C Schrader1, Marlene Barho, Iljana Steiner, Regina Ortmann, Martin Schlitzer.   

Abstract

There are quite a number of antimalarial compounds in different states of preclinical and clinical development. Among those in advanced stages, combinations of known drugs or new substances from drug classes already used in antimalarial therapy are predominant. More compounds with novel or even unknown mechanism of action are found among those compounds which are in less advanced stages of development.
Copyright © 2012 Elsevier GmbH. All rights reserved.

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Year:  2012        PMID： 22898490     DOI： 10.1016/j.ijmm.2012.07.009

Source DB:  PubMed          Journal:  Int J Med Microbiol        ISSN： 1438-4221            Impact factor:   3.473


  5 in total

1.  Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities.

Authors:  Hao Li; Wei Sun; Xiuli Huang; Xiao Lu; Paresma R Patel; Myunghoon Kim; Meghan J Orr; Richard M Fisher; Takeshi Q Tanaka; John C McKew; Anton Simeonov; Philip E Sanderson; Wei Zheng; Kim C Williamson; Wenwei Huang
Journal:  ACS Comb Sci       Date:  2017-10-27       Impact factor: 3.784

Review 2.  Enhancing the antimalarial activity of artesunate.

Authors:  J O Adebayo; H Tijjani; A P Adegunloye; A A Ishola; E A Balogun; S O Malomo
Journal:  Parasitol Res       Date:  2020-07-07       Impact factor: 2.289

3.  Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum.

Authors:  Thomas Weidner; Abed Nasereddin; Lutz Preu; Johann Grünefeld; Ron Dzikowski; Conrad Kunick
Journal:  Molecules       Date:  2016-02-17       Impact factor: 4.411

4.  In Vitro Effect of Methanolic Extract of Argemone mexicana against Trichomonas vaginalis.

Authors:  Joel Horacio Elizondo-Luevano; Julia Verde-Star; Azucena González-Horta; Rocío Castro-Ríos; Magda Elizabeth Hernández-García; Abelardo Chávez-Montes
Journal:  Korean J Parasitol       Date:  2020-04-30       Impact factor: 1.341

Review 5.  Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

Authors:  Adrian Martin Pohlit; Renata Braga Souza Lima; Gina Frausin; Luiz Francisco Rocha E Silva; Stefanie Costa Pinto Lopes; Carolina Borsoi Moraes; Pedro Cravo; Marcus Vinícius Guimarães Lacerda; André Machado Siqueira; Lucio H Freitas-Junior; Fabio Trindade Maranhão Costa
Journal:  Molecules       Date:  2013-08-02       Impact factor: 4.411
  5 in total

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