Literature DB >> 2289644

A simple score for the identification of patients at high risk of organic diseases of the colon in the family doctor consulting room. The Local IBS Study Group.

S Bellentani1, P Baldoni, S Petrella, C Tata, C Armocida, P Marchegiano, G Saccoccio, F Manenti.   

Abstract

In order to develop a scoring system for selecting patients at high risk of organic diseases of the colon, who would need a colonoscopy or a barium enema, we conducted a study with 14 GPs in the local health care district of Modena. Over one year, 254 consecutive patients who consulted their GP for chronic abdominal pain were asked to answer a guided questionnaire. A checklist of simple parameters suggestive of the presence of organic diseases of the colon was also registered by the GP. For the final diagnosis, the patients underwent either a colonoscopy or a barium enema. Data collected were analysed by means of a stepwise logistic regression analysis to obtain a weighted score for the diagnosis of either irritable bowel syndrome (score less than 0) or organic disease (score greater than 0). Out of the 25 parameters explored, six were significantly more common among patients with organic disease and weighted as positive score (namely ESR greater than 17 mm, first hour, history of blood in the stool, leukocytosis greater than 10,000 cm3, age greater than 45 years, slight fever and presence of neoplastic colonic diseases in first-degree relatives). On the contrary, five parameters were more frequent among patients with irritable bowel syndrome and weighted as negative score (namely visible distension of the abdomen, feeling of distension, presence of irritable bowel syndrome in first degree relatives, flatulence and irregularities of bowel movement). Our scoring system correctly classified 83.5% of the cases, and it was very sensitive (82.4%) for the diagnosis of organic disease.(ABSTRACT TRUNCATED AT 250 WORDS)

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Year:  1990        PMID: 2289644     DOI: 10.1093/fampra/7.4.307

Source DB:  PubMed          Journal:  Fam Pract        ISSN: 0263-2136            Impact factor:   2.267


  12 in total

1.  Familial aggregation of irritable bowel syndrome: a family case-control study.

Authors:  Yuri A Saito; Gloria M Petersen; Joseph J Larson; Elizabeth J Atkinson; Brooke L Fridley; Mariza de Andrade; G Richard Locke; Janice M Zimmerman; Ann E Almazar-Elder; Nicholas J Talley
Journal:  Am J Gastroenterol       Date:  2010-03-16       Impact factor: 10.864

Review 2.  Genetic approaches to functional gastrointestinal disorders.

Authors:  Yuri A Saito; Nandita Mitra; Emeran A Mayer
Journal:  Gastroenterology       Date:  2010-02-19       Impact factor: 22.682

Review 3.  The diagnostic value of symptoms for colorectal cancer in primary care: a systematic review.

Authors:  Margaret Astin; Tom Griffin; Richard D Neal; Peter Rose; William Hamilton
Journal:  Br J Gen Pract       Date:  2011-05       Impact factor: 5.386

4.  Organic colonic lesions in 3,332 patients with suspected irritable bowel syndrome and lacking warning signs, a retrospective case--control study.

Authors:  Hong-Xiang Gu; Ya-Li Zhang; Fa-Chao Zhi; Bo Jiang; Ying Huang
Journal:  Int J Colorectal Dis       Date:  2011-03-04       Impact factor: 2.571

Review 5.  Validation of symptom-based diagnostic criteria for irritable bowel syndrome: a critical review.

Authors:  William E Whitehead; Douglas A Drossman
Journal:  Am J Gastroenterol       Date:  2010-02-23       Impact factor: 10.864

6.  Patients with irritable bowel syndrome: health status and use of health care services.

Authors:  G A Donker; M Foets; P Spreeuwenberg
Journal:  Br J Gen Pract       Date:  1999-10       Impact factor: 5.386

Review 7.  The role of genetics in IBS.

Authors:  Yuri A Saito
Journal:  Gastroenterol Clin North Am       Date:  2011-03       Impact factor: 3.806

Review 8.  Value of symptoms and additional diagnostic tests for colorectal cancer in primary care: systematic review and meta-analysis.

Authors:  Petra Jellema; Daniëlle A W M van der Windt; David J Bruinvels; Christian D Mallen; Stijn J B van Weyenberg; Chris J Mulder; Henrica C W de Vet
Journal:  BMJ       Date:  2010-03-31

Review 9.  Genes and irritable bowel syndrome: is there a link?

Authors:  Yuri A Saito
Journal:  Curr Gastroenterol Rep       Date:  2008-08

10.  Irritable bowel syndrome aggregates strongly in families: a family-based case-control study.

Authors:  Y A Saito; J M Zimmerman; W S Harmsen; M De Andrade; G R Locke; G M Petersen; N J Talley
Journal:  Neurogastroenterol Motil       Date:  2008-07       Impact factor: 3.598

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