Literature DB >> 22895802

Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin.

Benno Hartung1, Hans F Merk, Wolfgang Huckenbeck, Thomas Daldrup, Eva Neuen-Jacob, Stefanie Ritz-Timme.   

Abstract

Isotretinoin is considered to be a safe and effective therapy in otherwise therapy-resistant acne. Elevated serum creatine phosphokinase values with or without muscle-related symptoms in isotretinoin-treated patients have been reported and interpreted as benign phenomena, lethal cases have not been described yet. We present the case of a 20-year-old male who died from severe generalised rhabdomyolysis associated with isotretinoin treatment.

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Year:  2012        PMID: 22895802     DOI: 10.1007/s00414-012-0750-2

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN: 0937-9827            Impact factor:   2.686


  21 in total

1.  Harmonization of medico-legal autopsy rules. Committee of Ministers. Council of Europe.

Authors:  B Brinkmann
Journal:  Int J Legal Med       Date:  1999       Impact factor: 2.686

2.  Treatment of acne with intermittent isotretinoin.

Authors:  V Goulden; S M Clark; C McGeown; W J Cunliffe
Journal:  Br J Dermatol       Date:  1997-07       Impact factor: 9.302

3.  Bio-medicolegal guidelines and protocols: survey and future perspectives in Europe.

Authors:  Santo Davide Ferrara; Thomas Bajanowski; Rossana Cecchi; Rossella Snenghi; Colette Case; Guido Viel
Journal:  Int J Legal Med       Date:  2010-06-12       Impact factor: 2.686

4.  Lethal thyroid storm after uncontrolled intake of liothyronine in order to lose weight.

Authors:  Benno Hartung; Matthias Schott; Thomas Daldrup; Stefanie Ritz-Timme
Journal:  Int J Legal Med       Date:  2010-02-10       Impact factor: 2.686

5.  Elevated creatine phosphokinase with isotretinoin.

Authors:  E I McBurney; D A Rosen
Journal:  J Am Acad Dermatol       Date:  1984-03       Impact factor: 11.527

Review 6.  Isotretinoin treatment of acne and related disorders: an update.

Authors:  A R Shalita; W J Cunningham; J J Leyden; P E Pochi; J S Strauss
Journal:  J Am Acad Dermatol       Date:  1983-10       Impact factor: 11.527

7.  Changes in plasma lipids and lipoproteins during isotretinoin therapy for acne.

Authors:  S Bershad; A Rubinstein; J R Paterniti; N A Le; S C Poliak; B Heller; H N Ginsberg; R Fleischmajer; W V Brown
Journal:  N Engl J Med       Date:  1985-10-17       Impact factor: 91.245

8.  Isotretinoin for acne vulgaris--10 years later: a safe and successful treatment.

Authors:  A M Layton; H Knaggs; J Taylor; W J Cunliffe
Journal:  Br J Dermatol       Date:  1993-09       Impact factor: 9.302

9.  Creatine phosphokinase values during isotretinoin treatment for acne.

Authors:  Yesim Kaymak
Journal:  Int J Dermatol       Date:  2008-04       Impact factor: 2.736

Review 10.  Bench-to-bedside review: Rhabdomyolysis -- an overview for clinicians.

Authors:  Ana L Huerta-Alardín; Joseph Varon; Paul E Marik
Journal:  Crit Care       Date:  2004-10-20       Impact factor: 9.097

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  6 in total

1.  Isotretinoin Associated Rhabdomyolysis: Monitoring Creatine Kinase and Educating Patients.

Authors:  Folasade F Fayiga; Sophia C Reyes-Hadsall; Ludonir C Sebastiany; Sergey Arutyunyan; Alan Wong; Ana M Duarte
Journal:  Skin Appendage Disord       Date:  2021-07-28

2.  Rhabdomyolysis Caused by Isotretinoin and Exercise in an Otherwise Healthy Female Patient.

Authors:  Eli Raneses; Eric C Schmidgal
Journal:  Cureus       Date:  2022-06-15

3.  Elevated creatine kinase levels, exercise, and isotretinoin for acne.

Authors:  Justin W Marson; Hilary E Baldwin
Journal:  JAAD Case Rep       Date:  2022-01-22

4.  High Neutrophil-to-Lymphocyte Ratio Facilitates Cancer Growth-Currently Marketed Drugs Tadalafil, Isotretinoin, Colchicine, and Omega-3 to Reduce It: The TICO Regimen.

Authors:  Richard E Kast
Journal:  Cancers (Basel)       Date:  2022-10-10       Impact factor: 6.575

5.  Myositis Induced by Isotretinoin: A Case Report and Literature Review.

Authors:  Julián Alejandro Rivillas; Víctor Alfonso Santos Andrade; Andrés Alberto Hormaza-Jaramillo
Journal:  Am J Case Rep       Date:  2020-01-20

6.  A Common Drug With a Dangerous Side Effect: Acute Rhabdomyolysis Caused by the Synergistic Effect of Isotretinoin and Exercise in an Adolescent.

Authors:  Kingshuk Dasgupta; Peter Lim; Hannah Reedstorm
Journal:  Cureus       Date:  2020-10-13
  6 in total

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