Literature DB >> 22895789

Metronidazole validates drugs targeting hypoxic bacteria for improved treatment of tuberculosis.

Ying Zhang1.   

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Year:  2012        PMID: 22895789      PMCID: PMC3435169          DOI: 10.1073/pnas.1211081109

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  20 in total

1.  Metronidazole therapy in mice infected with tuberculosis.

Authors:  J V Brooks; S K Furney; I M Orme
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques.

Authors:  Philana Ling Lin; Veronique Dartois; Paul J Johnston; Christopher Janssen; Laura Via; Michael B Goodwin; Edwin Klein; Clifton E Barry; Joanne L Flynn
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-23       Impact factor: 11.205

3.  Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis.

Authors:  Eric Nuermberger; Sandeep Tyagi; Rokeya Tasneen; Kathy N Williams; Deepak Almeida; Ian Rosenthal; Jacques H Grosset
Journal:  Antimicrob Agents Chemother       Date:  2008-02-19       Impact factor: 5.191

4.  Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates.

Authors:  Laura E Via; P Ling Lin; Sonja M Ray; Jose Carrillo; Shannon Sedberry Allen; Seok Yong Eum; Kimberly Taylor; Edwin Klein; Ujjini Manjunatha; Jacqueline Gonzales; Eun Gae Lee; Seung Kyu Park; James A Raleigh; Sang Nae Cho; David N McMurray; JoAnne L Flynn; Clifton E Barry
Journal:  Infect Immun       Date:  2008-03-17       Impact factor: 3.441

5.  Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis.

Authors:  Susan E Dorman; John L Johnson; Stefan Goldberg; Grace Muzanye; Nesri Padayatchi; Lorna Bozeman; Charles M Heilig; John Bernardo; Shurjeel Choudhri; Jacques H Grosset; Elizabeth Guy; Priya Guyadeen; Maria Corazon Leus; Gina Maltas; Dick Menzies; Eric L Nuermberger; Margarita Villarino; Andrew Vernon; Richard E Chaisson
Journal:  Am J Respir Crit Care Med       Date:  2009-04-30       Impact factor: 21.405

6.  Metronidazole lacks activity against Mycobacterium tuberculosis in an in vivo hypoxic granuloma model of latency.

Authors:  Lee G Klinkenberg; Lesley A Sutherland; William R Bishai; Petros C Karakousis
Journal:  J Infect Dis       Date:  2008-07-15       Impact factor: 5.226

7.  Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis.

Authors:  L G Wayne; H A Sramek
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

8.  Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis.

Authors:  Eric L Nuermberger; Tetsuyuki Yoshimatsu; Sandeep Tyagi; Kathy Williams; Ian Rosenthal; Richard J O'Brien; Andrew A Vernon; Richard E Chaisson; William R Bishai; Jacques H Grosset
Journal:  Am J Respir Crit Care Med       Date:  2004-08-11       Impact factor: 21.405

9.  Metronidazole has no antibacterial effect in Cornell model murine tuberculosis.

Authors:  J Dhillon; B W Allen; Y M Hu; A R Coates; D A Mitchison
Journal:  Int J Tuberc Lung Dis       Date:  1998-09       Impact factor: 2.373

10.  Microbial persistence.

Authors:  W McDERMOTT
Journal:  Yale J Biol Med       Date:  1958-02
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  1 in total

Review 1.  Types and functions of heterogeneity in mycobacteria.

Authors:  Eun Seon Chung; William C Johnson; Bree B Aldridge
Journal:  Nat Rev Microbiol       Date:  2022-04-01       Impact factor: 78.297

  1 in total

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