| Literature DB >> 22895216 |
Seigo Korematsu1, Yoko Ohta, Naotaka Tamai, Masahiro Takeguchi, Chika Goto, Hiroaki Miyahara, Tatsuya Kawano, Tatsuro Izumi.
Abstract
The interaction of matrix metalloproteinase (MMP)-9 and tissue inhibitor of matrix metalloproteinase-1 has been implicated in the formation of coronary aneurysms in Kawasaki disease. MMP-9 and tissue inhibitor of matrix metalloproteinase-1 were distributed predominantly in the granulocytes and platelets, respectively, in patients with Kawasaki disease. The plasma values of MMP-9 correlated positively with the circulating neutrophil count. Inhibiting the activity of granulocytes and maintaining the platelet activity might prevent coronary aneurysms.Entities:
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Year: 2012 PMID: 22895216 DOI: 10.1097/INF.0b013e31825ba6b3
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN: 0891-3668 Impact factor: 2.129