Fatima C Sequeira1, Sherry R Chemler. 1. Department of Chemistry, The State University of New York at Buffalo, Buffalo, New York 14260, USA.
Abstract
A new copper(II) 2-ethylhexanoate-promoted addition of an alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to excellent yields and diastereoselectivities.
A new copper(II) 2-ethylhexanoate-promoted addition of ann class="Chemical">alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to excellent yields and diastereoselectivities.
Authors: Ilyas A Berhane; Ameya S Burde; Jonathan J Kennedy-Ellis; Eva Zurek; Sherry R Chemler Journal: Chem Commun (Camb) Date: 2021-09-30 Impact factor: 6.065