Functionalized 1,4-benzothiazine: a versatile scaffold with diverse biological properties.

1,4-Benzothiazines are known to represent a class of medicinally important heterocyclic compounds which are extensively used in drug design. They have wide biological properties which qualify them as excellent scaffolds in therapeutic and medicinal research. Thus, many derivatives of this compound have been synthesized as target structures in novel drug development. Hence, the motivation for this present review was the known widespread application of the 1,4-benzothiazine scaffolds.