Literature DB >> 2289047

Isocratic high performance liquid chromatographic analysis of S-adenosylmethionine and S-adenosylhomocysteine in animal tissues: the effect of exposure to nitrous oxide.

T Bottiglieri1.   

Abstract

A simple isocratic high performance liquid chromatographic method for the simultaneous measurement of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in animal tissues is described. The direct injection of perchloric acid tissue extracts and rapid resolution of both compounds in a single run reduces any sampling and analytical errors in determining the SAM/SAH ratio, a measure of methylation reactions. The method has been used to determine changes in brain SAM/SAH ratios after exposure of rats to nitrous oxide.

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Year:  1990        PMID： 2289047     DOI： 10.1002/bmc.1130040606

Source DB:  PubMed          Journal:  Biomed Chromatogr        ISSN： 0269-3879            Impact factor:   1.902


  17 in total

1.  Betaine improves nonalcoholic fatty liver and associated hepatic insulin resistance: a potential mechanism for hepatoprotection by betaine.

Authors:  Elango Kathirvel; Kengathevy Morgan; Ganesh Nandgiri; Brian C Sandoval; Marie A Caudill; Teodoro Bottiglieri; Samuel W French; Timothy R Morgan
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-08-19       Impact factor: 4.052

2.  Enhanced hepatic cholesterol accumulation induced by maternal betaine exposure is associated with hypermethylation of CYP7A1 gene promoter.

Authors:  Nannan Zhao; Shu Yang; Yue Feng; Bo Sun; Ruqian Zhao
Journal:  Endocrine       Date:  2019-03-28       Impact factor: 3.633

3.  Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice.

Authors:  Ji Zhang; Diane E Handy; Yufang Wang; Guylaine Bouchard; Jacob Selhub; Joseph Loscalzo; Martin C Carey
Journal:  Hepatology       Date:  2011-06-23       Impact factor: 17.425

4.  Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.

Authors:  Bermans J Iskandar; Elias Rizk; Brenton Meier; Nithya Hariharan; Teodoro Bottiglieri; Richard H Finnell; David F Jarrard; Ruma V Banerjee; J H Pate Skene; Aaron Nelson; Nirav Patel; Carmen Gherasim; Kathleen Simon; Thomas D Cook; Kirk J Hogan
Journal:  J Clin Invest       Date:  2010-04-26       Impact factor: 14.808

5.  Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia.

Authors:  Melissa B Glier; Ying F Ngai; Dian C Sulistyoningrum; Rika E Aleliunas; Teodoro Bottiglieri; Angela M Devlin
Journal:  Epigenetics       Date:  2012-12-05       Impact factor: 4.528

6.  Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.

Authors:  Sanjana Dayal; Roman N Rodionov; Erland Arning; Teodoro Bottiglieri; Masumi Kimoto; Daryl J Murry; John P Cooke; Frank M Faraci; Steven R Lentz
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-06-20       Impact factor: 4.733

7.  CblE type of homocystinuria due to methionine synthase reductase deficiency: clinical and molecular studies and prenatal diagnosis in two families.

Authors:  P Zavadakova; B Fowler; J Zeman; T Suormala; K Pristoupilová; V Kozich; P Zavad'áková
Journal:  J Inherit Metab Dis       Date:  2002-10       Impact factor: 4.982

Review 8.  Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse.

Authors:  Eric O Uthus; Holly M Brown-Borg
Journal:  Mech Ageing Dev       Date:  2006-03-06       Impact factor: 5.432

9.  Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.

Authors:  Robert S Chapkin; Barton A Kamen; Evelyn S Callaway; Laurie A Davidson; Nysia I George; Naisyin Wang; Joanne R Lupton; Richard H Finnell
Journal:  J Nutr Biochem       Date:  2008-10-16       Impact factor: 6.048

10.  Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues.

Authors:  Jakub Krijt; Alena Dutá; Viktor Kozich
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2009-05-28       Impact factor: 3.205
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