| Literature DB >> 22888073 |
Jun Ge1, Evgenios Neofytou, Jiandu Lei, Ramin E Beygui, Richard N Zare.
Abstract
Amphiphilic bovine serum albumin-poly(methyl methacrylate) conjugate forms nanoparticles with the uniform size of ~100 nm by self-assembling. Loaded with the hydrophobic anti-tumor drug camptothecin, the nanoparticle efficiently delivers drugs into cancer cells, and thus inhibits ~79% of tumor growth in animals compared with free drug.Entities:
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Year: 2012 PMID: 22888073 DOI: 10.1002/smll.201200889
Source DB: PubMed Journal: Small ISSN: 1613-6810 Impact factor: 13.281