Literature DB >> 2288635

Growth hormone receptors in hypothalamic and extra-hypothalamic tissues.

R A Fraser1, D Attardo, S Harvey.   

Abstract

Central GH receptors (GHR) have been identified in hypothalamic and extra-hypothalamic tissues of rabbit and chicken brains. Plasma membranes of the rabbit brain demonstrated specific saturable high-affinity, low-capacity binding sites for 125I-labelled GH. RNA extracted from hypothalamic and extra-hypothalamic tissues of rabbit and chicken brains contained mRNA that hybridized with a cDNA probe for the rabbit liver GHR. This transcript was of a similar size to the major GHR mRNA moiety in rabbit liver. The expression of these moieties was age related, and higher in adult than in neonatal animals.

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Year:  1990        PMID： 2288635     DOI： 10.1677/jme.0.0050231

Source DB:  PubMed          Journal:  J Mol Endocrinol        ISSN： 0952-5041            Impact factor:   5.098


  5 in total

1.  Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats.

Authors:  Doris P Molina; Olusegun J Ariwodola; Constance Linville; William E Sonntag; Jeff L Weiner; Judy K Brunso-Bechtold; Michelle M Adams
Journal:  Neurobiol Aging       Date:  2011-10-19       Impact factor: 4.673

Review 2.  Growth hormone. A paracrine growth factor?

Authors:  S Harvey; K L Hull
Journal:  Endocrine       Date:  1997-12       Impact factor: 3.633

3.  Growth hormone receptor synthesis and release in tumorous somatolactotrophs.

Authors:  K L Hull; E J Sanders; S Harvey
Journal:  Endocrine       Date:  1995-06       Impact factor: 3.633

4.  Growth hormone (GH) action in the brain: neural expression of a GH-response gene.

Authors:  Steve Harvey; Irina Lavelin; Mark Pines
Journal:  J Mol Neurosci       Date:  2002 Feb-Apr       Impact factor: 3.444

5.  Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats.

Authors:  Doris P Molina; Olusegun J Ariwodola; Jeff L Weiner; Judy K Brunso-Bechtold; Michelle M Adams
Journal:  Age (Dordr)       Date:  2012-08-01
  5 in total

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