Literature DB >> 22885528

A two-hit model of autoimmunity: lymphopenia and unresponsiveness to TGF-β signaling.

Andrew L'Huillier1, Guangwen Ren, Yufang Shi, Jimin Zhang.   

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Year:  2012        PMID： 22885528      PMCID： PMC4002331          DOI： 10.1038/cmi.2012.25

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


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  9 in total

1.  Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms.

Authors:  Ming O Li; Shomyseh Sanjabi; Richard A Flavell
Journal:  Immunity       Date:  2006-09       Impact factor: 31.745

2.  Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

Authors:  M E Brunkow; E W Jeffery; K A Hjerrild; B Paeper; L B Clark; S A Yasayko; J E Wilkinson; D Galas; S F Ziegler; F Ramsdell
Journal:  Nat Genet       Date:  2001-01       Impact factor: 38.330

Review 3.  Autoimmunity during lymphopenia: a two-hit model.

Authors:  Tom Krupica; Terry J Fry; Crystal L Mackall
Journal:  Clin Immunol       Date:  2006-08       Impact factor: 3.969

4.  Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

Authors:  Cecile King; Alex Ilic; Kersten Koelsch; Nora Sarvetnick
Journal:  Cell       Date:  2004-04-16       Impact factor: 41.582

Review 5.  Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis.

Authors:  Eleonora Gambineri; Troy R Torgerson; Hans D Ochs
Journal:  Curr Opin Rheumatol       Date:  2003-07       Impact factor: 5.006

Review 6.  Transforming growth factor-beta regulation of immune responses.

Authors:  Ming O Li; Yisong Y Wan; Shomyseh Sanjabi; Anna-Karin L Robertson; Richard A Flavell
Journal:  Annu Rev Immunol       Date:  2006       Impact factor: 28.527

7.  TGF-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.

Authors:  Nu Zhang; Michael J Bevan
Journal:  Nat Immunol       Date:  2012-05-27       Impact factor: 25.606

8.  Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta.

Authors:  K Nakamura; A Kitani; W Strober
Journal:  J Exp Med       Date:  2001-09-03       Impact factor: 14.307

Review 9.  Lymphopenia and autoimmune diseases.

Authors:  Hendrik Schulze-Koops
Journal:  Arthritis Res Ther       Date:  2004-06-22       Impact factor: 5.156
  9 in total
  4 in total

1.  A novel subset of helper T cells promotes immune responses by secreting GM-CSF.

Authors:  J Zhang; A I Roberts; C Liu; G Ren; G Xu; L Zhang; S Devadas; Yufang Shi
Journal:  Cell Death Differ       Date:  2013-09-27       Impact factor: 15.828

2.  Host Genetics at the Intersection of Autoimmunity and COVID-19: A Potential Key for Heterogeneous COVID-19 Severity.

Authors:  Tugce Karaderi; Halin Bareke; Imge Kunter; Adil Seytanoglu; Ilgin Cagnan; Deniz Balci; Burc Barin; Mevhibe B Hocaoglu; Nilufer Rahmioglu; Esra Asilmaz; Bahar Taneri
Journal:  Front Immunol       Date:  2020-12-22       Impact factor: 7.561

Review 3.  Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity.

Authors:  Ting-Ting Sheu; Bor-Luen Chiang
Journal:  Int J Mol Sci       Date:  2021-04-16       Impact factor: 5.923

Review 4.  Immune Equilibrium Depends on the Interaction Between Recognition and Presentation Landscapes.

Authors:  Daniil Shevyrev; Valeriy Tereshchenko; Vladimir Kozlov
Journal:  Front Immunol       Date:  2021-07-30       Impact factor: 7.561
  4 in total

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