Literature DB >> 22884689

Secondary vaginoplasty for disorders for sexual differentiation: is there a right time? Challenges with compliance and follow-up at a multidisciplinary center.

Katie H Willihnganz-Lawson1, Sumit Isharwal, Jane M Lewis, Kyriakie Sarafoglou, Anne Boisclair-Fahey, Aseem R Shukla.   

Abstract

PURPOSE: We present the experience of a multidisciplinary center for disorders of sexual differentiation (DSD) in treating females requiring vaginoplasty. Specifically, we evaluate outcomes and compliance with follow-up protocols in patients undergoing secondary vaginoplasties. MATERIALS/
METHODS: We retrospectively reviewed consecutive DSD patients who underwent feminizing genitoplasties in 2006-2010. A subset of patients were instructed in vaginal self-dilation at time of secondary vaginoplasty. Through follow-up visits and administered questionnaires we assessed outcomes, compliance and overall satisfaction.
RESULTS: Twenty-two feminizing genitoplasties were completed during the study interval. There were no postoperative complications; average blood loss was 74 ml and mean length of stay was 3 days. Ten females underwent secondary vaginoplasty. The response rate to questionnaires was 5 of 9. Age of initiation for self-dilation ranged from 8 to 24 years. Initial compliance two months postoperatively was good, but diminished 12-24 months after surgery. Responses to the quality-of-life questionnaire were diverse, reflecting a range of patient ages and varied experiences.
CONCLUSION: A multidisciplinary, comprehensive approach is necessary to care for patients with DSD due to psychosexual, medical and reconstructive concerns. A secondary vaginoplasty to facilitate menarche and psychosocial concerns is feasible with minimal complications, though compliance and toleration with regard to post-surgical dilation regimens is variable.
Copyright © 2012 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Congenital adrenal hyperplasia; Disorders of sexual differentiation; Feminizing genitoplasty;; Self-dilation regimen; Vaginoplasty

Mesh:

Year:  2012        PMID: 22884689     DOI: 10.1016/j.jpurol.2012.06.015

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  3 in total

Review 1.  Multidisciplinary care for individuals with disorders of sex development.

Authors:  Veronica Gomez-Lobo
Journal:  Curr Opin Obstet Gynecol       Date:  2014-10       Impact factor: 1.927

2.  Clinical guidelines for the diagnosis and treatment of 21-hydroxylase deficiency (2021 revision).

Authors:  Tomohiro Ishii; Kenichi Kashimada; Naoko Amano; Kei Takasawa; Akari Nakamura-Utsunomiya; Shuichi Yatsuga; Tokuo Mukai; Shinobu Ida; Mitsuhisa Isobe; Masaru Fukushi; Hiroyuki Satoh; Kaoru Yoshino; Michio Otsuki; Takuyuki Katabami; Toshihiro Tajima
Journal:  Clin Pediatr Endocrinol       Date:  2022-04-10

3.  Techniques of Primary Vaginoplasty in Young Adults with Differences of Sex Development and Female Identification.

Authors:  Verena Ellerkamp; Kristin Katharina Rall; Juergen Schaefer; Sara Brucker; Joerg Fuchs
Journal:  J Clin Med       Date:  2022-06-27       Impact factor: 4.964

  3 in total

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