Literature DB >> 22883912

Misoprostol for prevention and treatment of postpartum hemorrhage: what do we know? What is next?

Sheila Raghavan1, Dina Abbas, Beverly Winikoff.   

Abstract

Misoprostol is an effective and safe uterotonic for the prevention and treatment of postpartum hemorrhage (PPH). A 600-μg oral dose of misoprostol has been shown to prevent PPH in community-based randomized controlled trials. An 800-μg sublingual dose of misoprostol appears to be a good first-line treatment for controlling PPH. Adverse effects after use of misoprostol for PPH prevention or treatment may include shivering and fever. These effects are transient, resolve on their own, and are not life threatening. Misoprostol can play an important role in settings with limited access to oxytocin, and where there is no other option for PPH care.
Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 22883912     DOI: 10.1016/j.ijgo.2012.03.013

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN: 0020-7292            Impact factor:   3.561


  5 in total

1.  No excuse for ignoring methodologically sound studies.

Authors:  Richard Derman; Christiana Care
Journal:  J R Soc Med       Date:  2012-11       Impact factor: 5.344

2.  A novel tamponade agent for management of post partum hemorrhage: adaptation of the Xstat mini-sponge applicator for obstetric use.

Authors:  Maria I Rodriguez; Jeffrey T Jensen; Kenton Gregory; Mary Bullard; Paul Longo; Jerry Heidel; Alison Edelman
Journal:  BMC Pregnancy Childbirth       Date:  2017-06-13       Impact factor: 3.007

3.  Implementing at-scale, community-based distribution of misoprostol tablets to mothers in the third stage of labor for the prevention of postpartum haemorrhage in Sokoto State, Nigeria: Early results and lessons learned.

Authors:  Nosakhare Orobaton; Jumare Abdulazeez; Dele Abegunde; Kamil Shoretire; Abubakar Maishanu; Nnenna Ikoro; Bolaji Fapohunda; Wapada Balami; Katherine Beal; Akeem Ganiyu; Ringpon Gwamzhi; Anne Austin
Journal:  PLoS One       Date:  2017-02-24       Impact factor: 3.240

4.  A Stalled Revolution? Misoprostol and the Pharmaceuticalization of Reproductive Health in Francophone Africa.

Authors:  Siri Suh
Journal:  Front Sociol       Date:  2021-04-12

5.  Misoprostol for the prevention of post-partum haemorrhage in Mozambique: an analysis of the interface between human rights, maternal health and development.

Authors:  Karen Hobday; Anthony B Zwi; Caroline Homer; Renae Kirkham; Jennifer Hulme; Páscoa Zualo Wate; Ndola Prata
Journal:  BMC Int Health Hum Rights       Date:  2020-04-08
  5 in total

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