Literature DB >> 22879846

Sentinel lymph node - work hypothesis in sinonasal carcinoma treatment.

Patricia Ene1, Radu Cristian Popescu, Stefan Voiculescu, Razvan Scaunasu, Bogdan Popescu, Raluca Grigore, Razvan Ene, Catalin Cârstoiu.   

Abstract

Although rare, sinonasal malignancies (SNM) can be lesions of immense importance. Approximately 60-70% of sinonasal malignancies (SNM) occur in the maxillary sinus and 20-30% occurs in the nasal cavity itself. The lymphatic drainage of the sinuses and nasal cavity include levels I-III as well as the parapharyngian nodes. Elective regional lymph node dissections became controversial because of overtreatment of the many patients without lymph node metastases. Lymphatic metastasis is the most important mechanism of spread in sinonasal squamous cell carcinoma considering the vast network of vessels in this area. The indications and type of neck dissection to be performed in the positive node neck and management of the N0 neck remain controversial. The sentinel lymph node concept is based on the Halsted theory that stressed the importance of locoregional cancer treatment because of the far site spread. Each patient with head and neck malignancies, including sinonasal carcinoma have about 2-3 sentinel lymph nodes of which up to 40% of them contain metastases.

Entities:  

Keywords:  N0 neck; regional lymph node; sentinel lymph node; sinonasal malignancies

Year:  2011        PMID: 22879846      PMCID: PMC3391949     

Source DB:  PubMed          Journal:  Maedica (Buchar)        ISSN: 1841-9038


  22 in total

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Journal:  Head Neck       Date:  2009-05       Impact factor: 3.147

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Authors:  Vishal U S Rao; Ashok M Shenoy
Journal:  Lancet Oncol       Date:  2010-03       Impact factor: 41.316

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Journal:  Head Neck       Date:  1989 Mar-Apr       Impact factor: 3.147

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Authors:  Robert D Hart; Joseph G Nasser; Jonathan R Trites; S Mark Taylor; Martin Bullock; David Barnes
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2005-01

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Journal:  Ann Otol Rhinol Laryngol       Date:  1967-12       Impact factor: 1.547

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Journal:  Am J Surg       Date:  1985-10       Impact factor: 2.565

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Authors:  Gary L Ross; David S Soutar; D Gordon MacDonald; Taimur Shoaib; Ivan Camilleri; Andrew G Roberton; Jens A Sorensen; Jorn Thomsen; Peter Grupe; Julio Alvarez; L Barbier; J Santamaria; Tito Poli; Olindo Massarelli; Enrico Sesenna; Adorján F Kovács; Frank Grünwald; Luigi Barzan; Sandro Sulfaro; Franco Alberti
Journal:  Ann Surg Oncol       Date:  2004-06-14       Impact factor: 5.344

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Journal:  Int J Radiat Oncol Biol Phys       Date:  2004-04-01       Impact factor: 7.038

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Authors:  R M Byers; P F Wolf; A J Ballantyne
Journal:  Head Neck Surg       Date:  1988 Jan-Feb
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  2 in total

Review 1.  Methods of investigating metastatic lymph nodes in head and neck cancer.

Authors:  Bogdan Popescu; Patricia Ene; Serban Vifor Gabriel Bertesteanu; Razvan Ene; Catalin Cirstoiu; Cristian Radu Popescu
Journal:  Maedica (Buchar)       Date:  2013-09

2.  Functional implications of radical neck dissection and the impact on the quality of life for patients with head and neck neoplasia.

Authors:  B Popescu; S V G Berteşteanu; R Grigore; R Scăunaşu; C R Popescu
Journal:  J Med Life       Date:  2012-12-25
  2 in total

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