Literature DB >> 22879002

The hairy-print for levamisole-induced vasculitis.

Hélène Lazareth1, Gilles Peytavin, Laura Polivka, Nicolas Dupin.   

Abstract

Levamisole-induced vasculitis is a well-characterised antineutrophil cytoplasm antibodies (ANCA)-positive vasculitis in cocaine abuser patients. However, due to the short half-life of levamisole in serum and urine, the causal role of levamisole is not established. Here we report the detection of both levamisole and cocaine in hair samples of a patient who presented with an ANCA-positive vasculitis. The higher concentration of levamisole in proximal sample of the hair confirms that the patient abused of cocaine added with levamisole in the days preceding the development of skin lesions. Although a direct causative role has not been established, our report strongly suggests that levamisole may have triggered vasculitis in this case.

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Year:  2012        PMID: 22879002      PMCID: PMC4544026          DOI: 10.1136/bcr-2012-006602

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Analysis of illicit cocaine and heroin samples seized in Luxembourg from 2005-2010.

Authors:  Serge Schneider; François Meys
Journal:  Forensic Sci Int       Date:  2011-07-20       Impact factor: 2.395

2.  A novel cutaneous vasculitis syndrome induced by levamisole-contaminated cocaine.

Authors:  Rachel L Gross; Jason Brucker; Asena Bahce-Altuntas; Maria A Abadi; Jules Lipoff; David Kotlyar; Peter Barland; Chaim Putterman
Journal:  Clin Rheumatol       Date:  2011-06-25       Impact factor: 2.980

3.  Cutaneous necrotising vasculitis induced by levamisole.

Authors:  M A Scheinberg; J B Bezerra; F A Almeida; L A Silveira
Journal:  Br Med J       Date:  1978-02-18

4.  Detection of levamisole exposure in cocaine users by liquid chromatography-tandem mass spectrometry.

Authors:  Kara L Lynch; Stephen S Dominy; Jonathan Graf; Alexander H Kral
Journal:  J Anal Toxicol       Date:  2011-04       Impact factor: 3.367

5.  Detection of drugs in human hair using Abbott ADx, with confirmation by gas chromatography/mass spectrometry (GC/MS).

Authors:  P Kintz; B Ludes; P Mangin
Journal:  J Forensic Sci       Date:  1992-01       Impact factor: 1.832

6.  Determination of levamisole in plasma and animal tissues by gas chromatography with thermionic specific detection.

Authors:  R Woestenborghs; L Michielsen; J Heykants
Journal:  J Chromatogr       Date:  1981-06-12
  6 in total
  4 in total

1.  Levamisole-contaminated cocaine: a hairy affair.

Authors:  Tjeerd van der Veer; Ed Pennings; J W Cohen Tervaert; Lindy-Anne Korswagen
Journal:  BMJ Case Rep       Date:  2015-08-26

Review 2.  Drug-induced glomerular disease: immune-mediated injury.

Authors:  Jonathan J Hogan; Glen S Markowitz; Jai Radhakrishnan
Journal:  Clin J Am Soc Nephrol       Date:  2015-06-19       Impact factor: 8.237

Review 3.  [Cocaine-induced vasculitis and mimics of vasculitis].

Authors:  Nikolas Ruffer; Martin Krusche; Konstanze Holl-Ulrich; Ina Kötter; Fabian Lötscher
Journal:  Z Rheumatol       Date:  2022-05-25       Impact factor: 1.372

Review 4.  DARK Classics in Chemical Neuroscience: Aminorex Analogues.

Authors:  Julian Maier; Felix P Mayer; Simon D Brandt; Harald H Sitte
Journal:  ACS Chem Neurosci       Date:  2018-10-05       Impact factor: 5.780

  4 in total

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