Literature DB >> 22878194

Specific 5-hydroxylation of piperlongumine by Beauveria bassiana ATCC 7159.

Jiachen Zi1, S Gabrielle Gladstone, Jixun Zhan.   

Abstract

A new hydroxylated derivative was efficiently prepared by transforming the natural anti-cancer product, piperlongumine, with Beauveria bassiana ATCC 7159. Its structure was determined to be 5-hydroxylpiperlongumine on the basis of the spectroscopic data. The absolute configuration at C-5 was established as R by Mosher's method.

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Year:  2012        PMID: 22878194     DOI: 10.1271/bbb.120223

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  1 in total

1.  Methylglucosylation of aromatic amino and phenolic moieties of drug-like biosynthons by combinatorial biosynthesis.

Authors:  Linan Xie; Liwen Zhang; Chen Wang; Xiaojing Wang; Ya-Ming Xu; Hefen Yu; Ping Wu; Shenglan Li; Lida Han; A A Leslie Gunatilaka; Xiaoyi Wei; Min Lin; István Molnár; Yuquan Xu
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-14       Impact factor: 11.205

  1 in total

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