Wen-Qiang Yang1, Hong-Cheng Wang, Wen-Jing Wang, Ying Wang, Xiao-Qi Zhang, Wen-Cai Ye. 1. Institute of Traditional Chinese Medicine & Natural Products,Jinan University /Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research,Jinan University, Guangzhou 510632, China.
Abstract
OBJECTIVE: To investigate the chemical constituents of the fruits of Areca catechu. METHODS: The chemical constituents were isolated by silica gel, RP-18 and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. RESULTS: Thirteen compounds were isolated from the 95% ethanol extract of the fruits of Areca catechu. Their structures were identified as isorhamnetin (1), quercetin (2), liquiritigenin (3), 5,7,4'-trihydroxy-3',5'-dimethoxyflavanone (4), (+)-catechin (5), resveratrol (6), ferulic acid (7), vanillic acid (8), 5,8-epidioxiergosta-6,22-dien-3beta-ol (9), stigmasta-4-en-3-one (10), beta-sitosterol (11), cycloartenol (12), and de-O-methyllasiodiplodin (13), respectively. CONCLUSION: Compounds 2-4,6,7,9,10, 12,13 are isolated from this plant for the first time.
OBJECTIVE: To investigate the chemical constituents of the fruits of Areca catechu. METHODS: The chemical constituents were isolated by silica gel, RP-18 and Sephadex LH-20 column chromatographies. Their structures were determined by chemical and spectroscopic methods. RESULTS: Thirteen compounds were isolated from the 95% ethanol extract of the fruits of Areca catechu. Their structures were identified as isorhamnetin (1), quercetin (2), liquiritigenin (3), 5,7,4'-trihydroxy-3',5'-dimethoxyflavanone (4), (+)-catechin (5), resveratrol (6), ferulic acid (7), vanillic acid (8), 5,8-epidioxiergosta-6,22-dien-3beta-ol (9), stigmasta-4-en-3-one (10), beta-sitosterol (11), cycloartenol (12), and de-O-methyllasiodiplodin (13), respectively. CONCLUSION: Compounds 2-4,6,7,9,10, 12,13 are isolated from this plant for the first time.