Literature DB >> 22876334

What's New in Transarterial Therapies for Hepatocellular Carcinoma?

Benjamin J May, Ravi Murthy, David C Madoff.   

Abstract

Transarterial therapies play an important role in the treatment of hepatocellular carcinoma, both in a palliative setting and as an adjunct to surgery. These therapies exploit the dual blood supply of the liver to selectively target tumors via the hepatic artery, while sparing nontumorous liver. Currently available therapies include transarterial embolization; chemoembolization, with or without drug-eluting beads; and radioembolization. Transarterial techniques are also being used in the development of novel therapies. This article provides an outline of the technical and clinical applications of intraarterial therapies in the treatment of HCC and highlights pertinent future directions.

Entities:  

Year:  2012        PMID: 22876334      PMCID: PMC3413029     

Source DB:  PubMed          Journal:  Gastrointest Cancer Res        ISSN: 1934-7820


  47 in total

1.  Safety and efficacy of transarterial chemoembolization in patients with unresectable hepatocellular carcinoma and portal vein thrombosis.

Authors:  Christos S Georgiades; Kelvin Hong; Michael D'Angelo; Jean-Francois H Geschwind
Journal:  J Vasc Interv Radiol       Date:  2005-12       Impact factor: 3.464

2.  The blood supply of neoplasms in the liver.

Authors:  C BREEDIS; G YOUNG
Journal:  Am J Pathol       Date:  1954 Sep-Oct       Impact factor: 4.307

3.  Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients.

Authors:  Kenichi Takayasu; Shigeki Arii; Iwao Ikai; Masao Omata; Kiwamu Okita; Takafumi Ichida; Yutaka Matsuyama; Yasuni Nakanuma; Masamichi Kojiro; Masatoshi Makuuchi; Yoshio Yamaoka
Journal:  Gastroenterology       Date:  2006-08       Impact factor: 22.682

Review 4.  p53 gene in treatment of hepatic carcinoma: status quo.

Authors:  Yong-Song Guan; Zi La; Lin Yang; Qing He; Ping Li
Journal:  World J Gastroenterol       Date:  2007-02-21       Impact factor: 5.742

Review 5.  Radioembolization with 90yttrium microspheres: a state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 2: special topics.

Authors:  Riad Salem; Kenneth G Thurston
Journal:  J Vasc Interv Radiol       Date:  2006-09       Impact factor: 3.464

6.  Intraarterial gene delivery in rabbit hepatic tumors: transfection with nonviral vector by using iodized oil emulsion.

Authors:  Young Il Kim; Jin Wook Chung; Jae Hyung Park; Joon Koo Han; Jung Wan Hong; Hesson Chung
Journal:  Radiology       Date:  2006-07-20       Impact factor: 11.105

7.  Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics.

Authors:  María Varela; María Isabel Real; Marta Burrel; Alejandro Forner; Margarita Sala; Mercé Brunet; Carmen Ayuso; Lluis Castells; Xavier Montañá; Josep M Llovet; Jordi Bruix
Journal:  J Hepatol       Date:  2006-11-29       Impact factor: 25.083

8.  Transcatheter arterial embolization with only particles for the treatment of unresectable hepatocellular carcinoma.

Authors:  Mary A Maluccio; Anne M Covey; Leah Ben Porat; Joanna Schubert; Lynn A Brody; Constantinos T Sofocleous; George I Getrajdman; William Jarnagin; Ronald Dematteo; Leslie H Blumgart; Yuman Fong; Karen T Brown
Journal:  J Vasc Interv Radiol       Date:  2008-04-10       Impact factor: 3.464

9.  A phase I/II trial of chemoembolization for hepatocellular carcinoma using a novel intra-arterial drug-eluting bead.

Authors:  Ronnie T P Poon; Wai Kuen Tso; Roberta W C Pang; Kelvin K C Ng; Regina Woo; Kin Shing Tai; Sheung Tat Fan
Journal:  Clin Gastroenterol Hepatol       Date:  2007-07-12       Impact factor: 11.382

10.  Liver transplantation for primary hepatic cancer.

Authors:  C E Haug; R L Jenkins; R J Rohrer; H Auchincloss; F L Delmonico; R B Freeman; W D Lewis; A B Cosimi
Journal:  Transplantation       Date:  1992-02       Impact factor: 4.939

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