Literature DB >> 22875730

The burden of pneumococcal pneumonia - experience of the German competence network CAPNETZ.

M W Pletz1, H von Baum, M van der Linden, G Rohde, H Schütte, N Suttorp, T Welte.   

Abstract

BACKGROUND: Pneumococcal pneumonia is still an important cause of mortality. The objective of this study was to compare frequency, clinical presentation, outcome and vaccination status of patients with pneumococcal community-acquired pneumonia (CAP) to CAP due to other or no detected pathogen based on data of the German Network for community-acquired pneumonia (CAPNETZ).
METHODS: Demographic, clinical and diagnostic data were recorded using standardized web-based data acquisition. Standardized microbiological sampling and work-up were conducted in each patient.
RESULTS: 7400 patients with CAP from twelve clinical centers throughout Germany were included. In 2259 patients (32 %) a pathogen was identified, Streptococcus pneumonia being the most frequent (n = 676, 30 % of all patients with identified pathogens). Compared to those with non-pneumococcal pneumonia, patients with pneumococcal pneumonia were more frequently admitted to hospital (80 % vs. 66 %, p < 0.001), had higher CURB score values on admission, had more frequently pleural effusion (19 % vs. 14 %, p = 0.001) and needed more frequently oxygen insufflation (58 % vs. 44 %, p < 0.001). There was no relevant difference in overall mortality.
CONCLUSIONS: Pneumococcal pneumonia was associated with a more severe clinical course demanding more medical resources as compared to non-pneumococcal pneumonia. © Georg Thieme Verlag KG Stuttgart · New York.

Entities:  

Mesh:

Year:  2012        PMID: 22875730     DOI: 10.1055/s-0032-1310103

Source DB:  PubMed          Journal:  Pneumologie        ISSN: 0934-8387


  26 in total

1.  [Pneumococcal vaccination for prevention of pneumonia].

Authors:  A Kwetkat; S Hagel; C Forstner; M W Pletz
Journal:  Z Gerontol Geriatr       Date:  2015-04-16       Impact factor: 1.281

2.  [Pneumococcus vaccination in immunosuppressed patients: current recommendations].

Authors:  A Krause; K Krüger
Journal:  Z Rheumatol       Date:  2013-12       Impact factor: 1.372

3.  [Prevention in the elderly: position paper on pneumococcal vaccinations. Results of an expert workshop on 15 November 2013 in Cologne, Germany].

Authors:  G Fätkenheuer; A Kwetkat; M W Pletz; J Schelling; R-J Schulz; M van der Linden; T Welte
Journal:  Z Gerontol Geriatr       Date:  2014-06       Impact factor: 1.281

4.  Modeling the cost-effectiveness of infant vaccination with pneumococcal conjugate vaccines in Germany.

Authors:  Alexander Kuhlmann; J-Matthias Graf von der Schulenburg
Journal:  Eur J Health Econ       Date:  2016-02-23

5.  Community-Acquired Pneumonia-an Underestimated Challenge.

Authors:  Tobias Welte
Journal:  Dtsch Arztebl Int       Date:  2016-09-16       Impact factor: 5.594

6.  Pneumococcal Conjugate Vaccine--Equally Effective for Everyone?

Authors:  Tobias Welte
Journal:  Dtsch Arztebl Int       Date:  2016-03-04       Impact factor: 5.594

7.  Localization and pneumococcal alteration of junction proteins in the human alveolar-capillary compartment.

Authors:  Andrea Peter; Diana Fatykhova; Olivia Kershaw; Achim D Gruber; Jens Rueckert; Jens Neudecker; Mario Toennies; Torsten T Bauer; Paul Schneider; Maria Schimek; Stephan Eggeling; Norbert Suttorp; Andreas C Hocke; Stefan Hippenstiel
Journal:  Histochem Cell Biol       Date:  2017-03-01       Impact factor: 4.304

8.  Pneumococcal vaccination rates in adults in Germany: an analysis of statutory health insurance data on more than 850,000 individuals.

Authors:  Ulrike Theidel; Alexander Kuhlmann; Anja Braem
Journal:  Dtsch Arztebl Int       Date:  2013-11-01       Impact factor: 5.594

9.  A retrospective analysis of hospital discharge records for S. pneumoniae diseases in the elderly population of Florence, Italy, 2010-2012.

Authors:  Angela Bechini; Cristina Taddei; Alessandro Barchielli; Miriam Levi; Emilia Tiscione; Maria Grazia Santini; Fabrizio Niccolini; Maria Teresa Mechi; Donatella Panatto; Daniela Amicizia; Chiara Azzari; Paolo Bonanni; Sara Boccalini
Journal:  Hum Vaccin Immunother       Date:  2014-11-01       Impact factor: 3.452

10.  [Vaccinations in respiratory medicine].

Authors:  H M Lode; R Stahlmann
Journal:  HNO       Date:  2015-09       Impact factor: 1.284

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