Literature DB >> 22874513

Thalidomide for steroid-dependent immune reconstitution inflammatory syndromes during AIDS.

Anne-Sophie Brunel1, Jacques Reynes, Edouard Tuaillon, Pierre-Alain Rubbo, Olivier Lortholary, Brigitte Montes, Vincent Le Moing, Alain Makinson.   

Abstract

Management of relapsing or refractory immune reconstitution inflammatory syndromes (IRISs) despite corticosteroid therapy is yet to be defined. We describe three HIV-infected patients with corticosteroid-dependent and life-threatening paradoxical immune reconstitution inflammatory syndrome for whom thalidomide treatment induced rapid clinical remission and permitted complete corticosteroid withdrawal without clinical relapse.

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Year:  2012        PMID： 22874513     DOI： 10.1097/QAD.0b013e328358daea

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  19 in total

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