Claire Infante-Rivard1, Federico Roncarolo, Kimberley Doucette. 1. Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, 1110 Avenue des Pins, Ouest, Montréal, QC H3A 1A, Canada. claire.infante-rivard@mcgill.ca
Abstract
PURPOSE: To investigate the reliability of family history of cancer reported by parents of children with acute lymphoblastic leukemia (ALL) and parents of healthy control children. METHODS: A total of 301 parents were selected based on positive or negative family history of cancer at baseline, case-control status, and gender of the respondent (mother or father). Baseline responses were compared with responses at the second interview using the same questionnaire. Reliability was measured using proportion of overall agreement, Cohen's kappa, and Cronbach's alpha; a logistic regression model was also used to assess the role of the case-control status on overall agreement as the dependent variable. RESULTS: The overall agreement between interviews was high and similar for cases (85 %) and controls (86 %); there were no consistent effects of respondent gender, age at first interview, or time elapsed between interviews on agreement measures. Agreement measures did not materially vary according to whether respondents were reporting about their mothers, fathers, or siblings. CONCLUSIONS: The study showed very good reliability of reporting family history among young parents of children affected with leukemia and parents of healthy control children.
PURPOSE: To investigate the reliability of family history of cancer reported by parents of children with acute lymphoblastic leukemia (ALL) and parents of healthy control children. METHODS: A total of 301 parents were selected based on positive or negative family history of cancer at baseline, case-control status, and gender of the respondent (mother or father). Baseline responses were compared with responses at the second interview using the same questionnaire. Reliability was measured using proportion of overall agreement, Cohen's kappa, and Cronbach's alpha; a logistic regression model was also used to assess the role of the case-control status on overall agreement as the dependent variable. RESULTS: The overall agreement between interviews was high and similar for cases (85 %) and controls (86 %); there were no consistent effects of respondent gender, age at first interview, or time elapsed between interviews on agreement measures. Agreement measures did not materially vary according to whether respondents were reporting about their mothers, fathers, or siblings. CONCLUSIONS: The study showed very good reliability of reporting family history among young parents of children affected with leukemia and parents of healthy control children.
Authors: Philip J Lupo; Heather E Danysh; Sharon E Plon; Karen Curtin; David Malkin; Simone Hettmer; Douglas S Hawkins; Stephen X Skapek; Logan G Spector; Karin Papworth; Beatrice Melin; Erik B Erhardt; Seymour Grufferman; Joshua D Schiffman Journal: Cancer Med Date: 2015-03-23 Impact factor: 4.452
Authors: Jit Chatterjee; Shilpa Sanapala; Olivia Cobb; Alice Bewley; Andrea K Goldstein; Elizabeth Cordell; Xia Ge; Joel R Garbow; Michael J Holtzman; David H Gutmann Journal: Nat Commun Date: 2021-12-08 Impact factor: 14.919