Literature DB >> 22870460

The role of synovitis in osteoarthritis.

Claire Y J Wenham1, Philip G Conaghan.   

Abstract

Osteoarthritis (OA) is the most common form of arthritis worldwide yet there is still a lack of effective treatments for this condition. Increasingly, attention has turned to the role of the synovium in OA as it is now recognized, in part from the use of modern imaging techniques, that synovitis is both common and associated with pain. This offers a target for treatment, for both symptom and potential structure modification. In this review we discuss the evidence for histological and imaging-detected synovitis and the current role of antisynovial therapies in OA.

Entities:  

Keywords:  histology; magnetic resonance imaging; osteoarthritis; synovitis; ultrasound

Year:  2010        PMID: 22870460      PMCID: PMC3383490          DOI: 10.1177/1759720X10378373

Source DB:  PubMed          Journal:  Ther Adv Musculoskelet Dis        ISSN: 1759-720X            Impact factor:   5.346


  63 in total

Review 1.  Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets.

Authors:  J P Pelletier; J Martel-Pelletier; S B Abramson
Journal:  Arthritis Rheum       Date:  2001-06

2.  Fluoroscopically directed steroid instillation in the treatment of hip osteoarthritis: safety and efficacy in 510 cases.

Authors:  K R Margules
Journal:  Arthritis Rheum       Date:  2001-10

Review 3.  Intra-articular treatments in osteoarthritis: from the symptomatic to the structure modifying.

Authors:  L Gossec; M Dougados
Journal:  Ann Rheum Dis       Date:  2004-05       Impact factor: 19.103

4.  Intra-articular treatment of hip osteoarthritis: a randomized trial of hyaluronic acid, corticosteroid, and isotonic saline.

Authors:  E Qvistgaard; R Christensen; S Torp-Pedersen; H Bliddal
Journal:  Osteoarthritis Cartilage       Date:  2005-11-14       Impact factor: 6.576

5.  Effect of intraarticular osmic acid on synovial membrane volume and inflammation, determined by magnetic resonance imaging.

Authors:  M Ostergaard; M Stoltenberg; P Gideon; S Wieslander; S Sonne-Holm; P Kryger; M Sonne
Journal:  Scand J Rheumatol       Date:  1995       Impact factor: 3.641

6.  Synovial tissue inflammation in early and late osteoarthritis.

Authors:  M J Benito; D J Veale; O FitzGerald; W B van den Berg; B Bresnihan
Journal:  Ann Rheum Dis       Date:  2005-02-24       Impact factor: 19.103

7.  Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease.

Authors:  T D Spector; D J Hart; D Nandra; D V Doyle; N Mackillop; J R Gallimore; M B Pepys
Journal:  Arthritis Rheum       Date:  1997-04

8.  A randomised controlled trial of intra-articular corticosteroid injection of the carpometacarpal joint of the thumb in osteoarthritis.

Authors:  G K Meenagh; J Patton; C Kynes; G D Wright
Journal:  Ann Rheum Dis       Date:  2004-10       Impact factor: 19.103

9.  Inflammation and angiogenesis in osteoarthritis.

Authors:  L Haywood; D F McWilliams; C I Pearson; S E Gill; A Ganesan; D Wilson; D A Walsh
Journal:  Arthritis Rheum       Date:  2003-08

10.  Synovial membrane histology and immunopathology in rheumatoid arthritis and osteoarthritis. In vivo effects of antirheumatic drugs.

Authors:  B Haraoui; J P Pelletier; J M Cloutier; M P Faure; J Martel-Pelletier
Journal:  Arthritis Rheum       Date:  1991-02
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  37 in total

1.  Anti-inflammatory Effect of DNA Polymeric Molecules in a Cell Model of Osteoarthritis.

Authors:  Ahreum Baek; MinGi Kim; Sung Hoon Kim; Sung-Rae Cho; Hyun Jung Kim
Journal:  Inflammation       Date:  2018-03       Impact factor: 4.092

2.  Serum and synovial fluid C-reactive protein level variations in dogs with degenerative joint disease and their relationships with physiological parameters.

Authors:  S Boal; L Miguel Carreira
Journal:  Vet Res Commun       Date:  2015-07-16       Impact factor: 2.459

3.  Advanced Hemophilic Arthropathy: Sensitivity of Soft Tissue Discrimination With Musculoskeletal Ultrasound.

Authors:  Annette von Drygalski; Randy E Moore; Sonha Nguyen; Richard F W Barnes; Lena M Volland; Tudor H Hughes; Jiang Du; Eric Y Chang
Journal:  J Ultrasound Med       Date:  2018-01-24       Impact factor: 2.153

4.  Efficacy of double inversion recovery magnetic resonance imaging for the evaluation of the synovium in the femoro-patellar joint without contrast enhancement.

Authors:  Ye Na Son; Wook Jin; Geon-Ho Jahng; Jang Gyu Cha; Yong Sung Park; Seong Jong Yun; So Young Park; Ji Seon Park; Kyung Nam Ryu
Journal:  Eur Radiol       Date:  2017-08-21       Impact factor: 5.315

5.  Pharmacokinetic Profile of Intra-articular Fluticasone Propionate Microparticles in Beagle Dog Knees.

Authors:  Alan Getgood; Aad Dhollander; Amanda Malone; James Price; James Helliwell
Journal:  Cartilage       Date:  2017-08-08       Impact factor: 4.634

Review 6.  Calcitonin gene-related peptide in the joint: contributions to pain and inflammation.

Authors:  David A Walsh; Paul I Mapp; Sara Kelly
Journal:  Br J Clin Pharmacol       Date:  2015-07-22       Impact factor: 4.335

7.  Levels of Matrix-Degrading Enzymes and Lubricin in Patients With Degenerative Joint Disease Requiring Arthroplasty.

Authors:  Christopher Wanderling; Jeffrey Liles; Elissa Davis; Daniel Schmitt; Stephen Statz; Nil Guler; Debra Hoppensteadt; Jawed Fareed; William Hopkinson
Journal:  Clin Appl Thromb Hemost       Date:  2017-09-07       Impact factor: 2.389

8.  Synovitis in knee osteoarthritis: a precursor of disease?

Authors:  I Atukorala; C K Kwoh; A Guermazi; F W Roemer; R M Boudreau; M J Hannon; D J Hunter
Journal:  Ann Rheum Dis       Date:  2014-12-08       Impact factor: 19.103

9.  [Intra-articular injection of ascorbic acid/ferric chloride relieves cartilage degradation in rats with osteoarthritis].

Authors:  Zhenting Liao; Zhenquan Xing; Yufan Chen; Zhonghao Deng; Desheng Wu; Liang Zhao
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-01-30

10.  cAMP attenuates TGF-β's profibrotic responses in osteoarthritic synoviocytes: involvement of hyaluronan and PRG4.

Authors:  Marwa M Qadri; Gregory D Jay; Rennolds S Ostrom; Ling X Zhang; Khaled A Elsaid
Journal:  Am J Physiol Cell Physiol       Date:  2018-06-13       Impact factor: 4.249

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