Literature DB >> 22866921

Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells.

Kumudha Balakrishnan, Sumesh Aggarwal, William Wierda, Varsha Gandhi.   

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Year:  2012        PMID： 22866921      PMCID： PMC4123740          DOI： 10.3109/10428194.2012.718344

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


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  21 in total

1.  Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.

Authors:  Shinichi Kitada; Marilisa Leone; Sina Sareth; Dayong Zhai; John C Reed; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2003-09-25       Impact factor: 7.446

2.  Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.

Authors:  S Kitada; J Andersen; S Akar; J M Zapata; S Takayama; S Krajewski; H G Wang; X Zhang; F Bullrich; C M Croce; K Rai; J Hines; J C Reed
Journal:  Blood       Date:  1998-05-01       Impact factor: 22.113

3.  X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.

Authors:  S W Muchmore; M Sattler; H Liang; R P Meadows; J E Harlan; H S Yoon; D Nettesheim; B S Chang; C B Thompson; S L Wong; S L Ng; S W Fesik
Journal:  Nature       Date:  1996-05-23       Impact factor: 49.962

4.  Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions.

Authors:  P Zhou; L Qian; K M Kozopas; R W Craig
Journal:  Blood       Date:  1997-01-15       Impact factor: 22.113

5.  Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia.

Authors:  Susan M O'Brien; Charles C Cunningham; Anatoliy K Golenkov; Anna G Turkina; Steven C Novick; Kanti R Rai
Journal:  J Clin Oncol       Date:  2005-09-26       Impact factor: 44.544

6.  Antisense-mediated suppression of Bcl-2 highlights its pivotal role in failed apoptosis in B-cell chronic lymphocytic leukaemia.

Authors:  C Pepper; A Thomas; T Hoy; F Cotter; P Bentley
Journal:  Br J Haematol       Date:  1999-12       Impact factor: 6.998

7.  Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.

Authors:  D Hockenbery; G Nuñez; C Milliman; R D Schreiber; S J Korsmeyer
Journal:  Nature       Date:  1990-11-22       Impact factor: 49.962

8.  Bax and Bak independently promote cytochrome C release from mitochondria.

Authors:  Kurt Degenhardt; Ramya Sundararajan; Tullia Lindsten; Craig Thompson; Eileen White
Journal:  J Biol Chem       Date:  2002-02-08       Impact factor: 5.157

9.  Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.

Authors:  Sunga Choi; Shivendra V Singh
Journal:  Cancer Res       Date:  2005-03-01       Impact factor: 12.701

10.  Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

Authors:  Barbara Becattini; Shinichi Kitada; Marilisa Leone; Edward Monosov; Sharon Chandler; Dayong Zhai; Thomas J Kipps; John C Reed; Maurizio Pellecchia
Journal:  Chem Biol       Date:  2004-03
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  8 in total

Review 1.  Bcl-2 antagonists: a proof of concept for CLL therapy.

Authors:  Kumudha Balakrishnan; Varsha Gandhi
Journal:  Invest New Drugs       Date:  2013-08-02       Impact factor: 3.850

Review 2.  Targeting the apoptosis pathway in hematologic malignancies.

Authors:  Shadia Zaman; Rui Wang; Varsha Gandhi
Journal:  Leuk Lymphoma       Date:  2014-02-04

3.  Cladribine, gemcitabine, busulfan, and SAHA combination as a potential pretransplant conditioning regimen for lymphomas: A preclinical study.

Authors:  Jie Ji; Benigno C Valdez; Yang Li; Yan Liu; Esmeralda C Teo; Yago Nieto; Richard E Champlin; Borje S Andersson
Journal:  Exp Hematol       Date:  2016-03-11       Impact factor: 3.084

4.  Herbal compound Naoshuantong capsule attenuates retinal injury in ischemia/reperfusion rat model by inhibiting apoptosis.

Authors:  Chuangxin Huang; Yang Gao; Qiang Yu; Liangqi Feng
Journal:  Int J Clin Exp Med       Date:  2015-08-15

5.  Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).

Authors:  Jens Mani; Stefan Vallo; Stefanie Rakel; Patrick Antonietti; Florian Gessler; Roman Blaheta; Georg Bartsch; Martin Michaelis; Jindrich Cinatl; Axel Haferkamp; Donat Kögel
Journal:  BMC Cancer       Date:  2015-04-07       Impact factor: 4.430

6.  Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study.

Authors:  Ruinian Zheng; Kexu Chen; Yu Zhang; Jie Huang; Fengrong Shi; Gang Wu; Senming Wang
Journal:  Oncol Lett       Date:  2017-05-16       Impact factor: 2.967

Review 7.  Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer.

Authors:  Natalie Yan Li Ngoi; Clarice Choong; Joanne Lee; Gregory Bellot; Andrea Li Ann Wong; Boon Cher Goh; Shazib Pervaiz
Journal:  Cancers (Basel)       Date:  2020-03-02       Impact factor: 6.639

Review 8.  Apoptosis inducers in chronic lymphocytic leukemia.

Authors:  Christian Billard
Journal:  Oncotarget       Date:  2014-01-30
  8 in total

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