Literature DB >> 22864843

[Long-term prescription of benzodiazepines and non-benzodiazepines].

U Verthein1, M S Martens, P Raschke, R Holzbach.   

Abstract

BACKGROUND: The number of persons with a dependence on prescription drugs such as sedatives or tranquilizers in Germany is estimated at between 1.4 and 1.9 million. According to national addiction treatment documentations only very few of them seek help in specialised treatment services. The majority of prescription drug-dependent people use benzodiazepines. This medication is usually prescribed by physicians and according to German guidelines it should be prescribed only for limited, short periods and in low doses.
OBJECTIVE: This study aims to determine the extent of the problematic prescription of benzodiazepines and non-benzodiazepines.
METHODS: We used prescription data from the Northern Germany Computing Centre for Pharmacies registered between 2005 and 2007. For the German regions of Hamburg, Bremen and Schleswig-Holstein, benzodiazepine prescriptions during an individual prospective period of 12 months were analysed.
RESULTS: From July 2005 to June 2006, 294 143 prescriptions of benzodiazepines and non-benzodiazepines were recorded for 78 456 citizens of Hamburg and billed at the expenses of the governmental health insurance funds. In the course of one observed patient year, 51.1% of benzodiazepine prescriptions were in accordance with the German guidelines. 15.6% of the patients were supplied on a long-term basis (0.5-1 DDD during at least 2 months). Prescriptions for women and persons older than 70 years were disproportionately high. Compared with the Federal states of Bremen and Schleswig-Holstein, Hamburg does not show an exceptional position.
CONCLUSION: The prescription of benzodiazepines which is not in accordance with the relevant national guidelines is widespread and calls for discussion and education among physicians and pharmacists. Furthermore, professional addiction services should reconsider ways to help and attract prescription drug-dependent people to cover their needs, as their numbers will grow in an aging society. © Georg Thieme Verlag KG Stuttgart · New York.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 22864843     DOI: 10.1055/s-0032-1321756

Source DB:  PubMed          Journal:  Gesundheitswesen        ISSN: 0941-3790


  4 in total

Review 1.  The problems of long-term treatment with benzodiazepines and related substances.

Authors:  Katrin Janhsen; Patrik Roser; Knut Hoffmann
Journal:  Dtsch Arztebl Int       Date:  2015-01-05       Impact factor: 5.594

2.  [Benzodiazepine hypnotics, zolpidem and zopiclone on private prescriptions: use between 1993 and 2012].

Authors:  F Hoffmann; G Glaeske
Journal:  Nervenarzt       Date:  2014-11       Impact factor: 1.214

3.  Potentially inappropriate use of benzodiazepines and z-drugs in the older population-analysis of associations between long-term use and patient-related factors.

Authors:  Aliaksandra Mokhar; Niklas Tillenburg; Jörg Dirmaier; Silke Kuhn; Martin Härter; Uwe Verthein
Journal:  PeerJ       Date:  2018-05-22       Impact factor: 2.984

4.  Trends in risky prescriptions of opioid analgesics from 2011 to 2015 in Northern Germany.

Authors:  Uwe Verthein; Sven Buth; Anne Daubmann; Marcus-Sebastien Martens; Bernd Schulte
Journal:  J Psychopharmacol       Date:  2020-07-17       Impact factor: 4.153

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.