Literature DB >> 22864235

Construction of α-amido-indanones via formal allenamide hydroacylation-Nazarov cyclization.

Yen-Ku Wu1, Tianmin Niu, F G West.   

Abstract

A two-step modular synthesis of an α-hydroxycyclopentenone and α-amido-indanones has been developed based on the Nazarov cyclization of 2-amido-1,4-pentadien-3-ones, readily accessed via formal hydroacylation of allenamides.

Entities:  

Year:  2012        PMID： 22864235     DOI： 10.1039/c2cc34644c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Diastereospecific nazarov cyclization of fully substituted dienones: generation of vicinal all-carbon-atom quaternary stereocenters.

Authors:  Anais Jolit; Saleta Vazquez-Rodriguez; Glenn P A Yap; Marcus A Tius
Journal:  Angew Chem Int Ed Engl       Date:  2013-09-03       Impact factor: 15.336

2.  α-Aryl-substituted allenamides in an imino-Nazarov cyclization cascade catalyzed by Au(I).

Authors:  Zhi-Xiong Ma; Shuzhong He; Wangze Song; Richard P Hsung
Journal:  Org Lett       Date:  2012-11-02       Impact factor: 6.005

Review 3.  Allenamides: a powerful and versatile building block in organic synthesis.

Authors:  Ting Lu; Zhenjie Lu; Zhi-Xiong Ma; Yu Zhang; Richard P Hsung
Journal:  Chem Rev       Date:  2013-04-04       Impact factor: 60.622
  3 in total

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