AIM: To evaluate outcomes of deep anterior lamellar keratoplasty (DALK) in keratoconic eyes with previous hydrops. METHODS: In this retrospective, non-comparative study, keratoconic eyes with previous hydrops that underwent DALK were included. DALK was performed using a modification of Melles's technique of optical recognition with pre-Descemet's membrane dissection. Data on preoperative and postoperative uncorrected distance visual acuity and best spectacle corrected distance visual acuity (BSCVA), postoperative spherical equivalent (SEQ); keratometry and adverse events were recorded for all eyes. RESULTS: Ten eyes (10 patients) underwent DALK in keratoconic eyes with previous hydrops. Mean follow-up was 56.4 ± 23.8 months. Preoperatively BSCVA was 6/24 or worse in all eyes. At last follow-up, 100% had BSCVA of 6/12 or better. Intraoperative microperforation at the site of previous hydrops occurred in six eyes but none required conversion to penetrating keratoplasty. At latest follow-up, mean SEQ was -2.4 ± 4.2D, keratometric astigmatism was 3.8 ± 1.6D and refractive astigmatism was 3.4 ± 2.2D. Mean postoperative keratometry was 43.7 ± 2.6 and central pachymetry 572.6 ± 65.0 µm. CONCLUSIONS: DALK in keratoconic corneas with prior hydrops is a safe and effective option that preserves host endothelium Intraoperative microperforations at the site of hydrops are common, however with good management favourable outcomes are possible.
AIM: To evaluate outcomes of deep anterior lamellar keratoplasty (DALK) in keratoconic eyes with previous hydrops. METHODS: In this retrospective, non-comparative study, keratoconic eyes with previous hydrops that underwent DALK were included. DALK was performed using a modification of Melles's technique of optical recognition with pre-Descemet's membrane dissection. Data on preoperative and postoperative uncorrected distance visual acuity and best spectacle corrected distance visual acuity (BSCVA), postoperative spherical equivalent (SEQ); keratometry and adverse events were recorded for all eyes. RESULTS: Ten eyes (10 patients) underwent DALK in keratoconic eyes with previous hydrops. Mean follow-up was 56.4 ± 23.8 months. Preoperatively BSCVA was 6/24 or worse in all eyes. At last follow-up, 100% had BSCVA of 6/12 or better. Intraoperative microperforation at the site of previous hydrops occurred in six eyes but none required conversion to penetrating keratoplasty. At latest follow-up, mean SEQ was -2.4 ± 4.2D, keratometric astigmatism was 3.8 ± 1.6D and refractive astigmatism was 3.4 ± 2.2D. Mean postoperative keratometry was 43.7 ± 2.6 and central pachymetry 572.6 ± 65.0 µm. CONCLUSIONS: DALK in keratoconic corneas with prior hydrops is a safe and effective option that preserves host endothelium Intraoperative microperforations at the site of hydrops are common, however with good management favourable outcomes are possible.
Authors: Alexander Händel; Jan Niklas Lüke; Sebastian Siebelmann; Jeremy Franklin; Sigrid Roters; Mario Matthaei; Björn O Bachmann; Claus Cursiefen; Deniz Hos Journal: Graefes Arch Clin Exp Ophthalmol Date: 2022-04-07 Impact factor: 3.535