Literature DB >> 22858266

A systematic review of resting-state functional-MRI studies in major depression.

L Wang1, D F Hermens, I B Hickie, J Lagopoulos.   

Abstract

BACKGROUND: To evaluate the literature pertaining to the use of resting-state functional magnetic resonance imaging (fMRI) in Major Depression (MD).
METHODS: A search for papers published in English was conducted using MedLine, Embase, PsycINFO, OvidSP, and ScienceDirect with the following words: resting state, depression, MRI, affective, and default-mode.
RESULTS: The findings from 16 resting-state fMRI studies on MD are tabulated. Some common findings are discussed in further detail.
CONCLUSION: The use of resting-state fMRI in MD research has yielded a number of significant findings that provide the basis for understanding the pathophysiology of depressive symptoms. Of particular note and deserving of further research are the roles of the cortico-limbic mood regulating circuit (MRC) and the interaction between task-positive and task-negative networks in MD. There is increasing interest in the use of resting-state fMRI in the study of psychiatric conditions, and continued improvement in technique and methodology will prove valuable in future research.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22858266     DOI: 10.1016/j.jad.2012.04.013

Source DB:  PubMed          Journal:  J Affect Disord        ISSN: 0165-0327            Impact factor:   4.839


  105 in total

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5.  Orbital and Medial Prefrontal Cortex Functional Connectivity of Major Depression Vulnerability and Disease.

Authors:  Zoe Samara; Elisabeth A T Evers; Frenk Peeters; Harry B M Uylings; Grazyna Rajkowska; Johannes G Ramaekers; Peter Stiers
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Authors:  Jaclyn Schwartz; Sarah J Ordaz; Katharina Kircanski; Tiffany C Ho; Elena G Davis; M Catalina Camacho; Ian H Gotlib
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7.  Group differences in MEG-ICA derived resting state networks: Application to major depressive disorder.

Authors:  Allison C Nugent; Stephen E Robinson; Richard Coppola; Maura L Furey; Carlos A Zarate
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