Literature DB >> 2285290

Characterization of mechanisms of resistance to beta-lactam antibiotics in methicillin-resistant strains of Staphylococcus saprophyticus.

C W Stratton1, M S Gelfand, J L Gerberding, H F Chambers.   

Abstract

The resistance mechanisms of methicillin-resistant strains of Staphylococcus saprophyticus were characterized. Penicillin-binding protein (PBP) studies demonstrated an inducible PBP identical to PBP 2a in the membranes of these isolates. The amount of beta-lactamase produced was minimal. PBP 2a is responsible for the methicillin resistance observed in these strains of S. saprophyticus.

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Year:  1990        PMID: 2285290      PMCID: PMC171924          DOI: 10.1128/AAC.34.9.1780

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  27 in total

1.  Differences in antibiotic susceptibility between Staphylococcus epidermidis and Staphylococcus saprophyticus.

Authors:  J F Richardson; R R Marples
Journal:  J Antimicrob Chemother       Date:  1980-07       Impact factor: 5.790

2.  Comparison of the Staph-Ident system with a conventional method for species identification of urine and blood isolates of coagulase-negative staphylococci.

Authors:  K E Aldridge; C W Stratton; L S Patterson; M E Evans; R L Hodges
Journal:  J Clin Microbiol       Date:  1983-03       Impact factor: 5.948

3.  Comparison of antimicrobial susceptibility patterns among coagulase-negative staphylococci.

Authors:  S B Price; D J Flournoy
Journal:  Antimicrob Agents Chemother       Date:  1982-03       Impact factor: 5.191

4.  Antimicrobial susceptibility of Staphylococcus saprophyticus and urethral staphylococci.

Authors:  T J Marrie; C Kwan
Journal:  Antimicrob Agents Chemother       Date:  1982-09       Impact factor: 5.191

5.  Susceptibility of clinical isolates of Staphylococcus saprophyticus to fifteen commonly used antimicrobial agents.

Authors:  L E Nicolle; G K Harding
Journal:  Antimicrob Agents Chemother       Date:  1982-11       Impact factor: 5.191

6.  Urinary tract infection caused by Staphylococcus saprophyticus.

Authors:  P A Jordan; A Iravani; G A Richard; H Baer
Journal:  J Infect Dis       Date:  1980-10       Impact factor: 5.226

7.  Urinary tract infections in young adult women caused by Staphylococcus saprophyticus.

Authors:  R H Latham; K Running; W E Stamm
Journal:  JAMA       Date:  1983-12-09       Impact factor: 56.272

8.  Use of extracts versus whole-cell bacterial suspensions in the identification of Staphylococcus aureus beta-lactamase variants.

Authors:  D S Kernodle; P A McGraw; C W Stratton; A B Kaiser
Journal:  Antimicrob Agents Chemother       Date:  1990-03       Impact factor: 5.191

9.  Staphylococcus saprophyticus: a frequent cause of acute urinary tract infection among female outpatients.

Authors:  G Wallmark; I Arremark; B Telander
Journal:  J Infect Dis       Date:  1978-12       Impact factor: 5.226

10.  Staphylococcus saprophyticus as a cause of urinary tract infections.

Authors:  T J Marrie; C Kwan; M A Noble; A West; L Duffield
Journal:  J Clin Microbiol       Date:  1982-09       Impact factor: 5.948

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  6 in total

1.  Methicillin-resistant Staphylococcus aureus disease in a Portuguese hospital: characterization of clonal types by a combination of DNA typing methods.

Authors:  H de Lencastre; I Couto; I Santos; J Melo-Cristino; A Torres-Pereira; A Tomasz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1994-01       Impact factor: 3.267

2.  Comparison of PCR detection of mecA with standard susceptibility testing methods to determine methicillin resistance in coagulase-negative staphylococci.

Authors:  M K York; L Gibbs; F Chehab; G F Brooks
Journal:  J Clin Microbiol       Date:  1996-02       Impact factor: 5.948

3.  Survey of methicillin-resistant clinical strains of coagulase-negative staphylococci for mecA gene distribution.

Authors:  E Suzuki; K Hiramatsu; T Yokota
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191

4.  Distribution of mec regulator genes in methicillin-resistant Staphylococcus clinical strains.

Authors:  E Suzuki; K Kuwahara-Arai; J F Richardson; K Hiramatsu
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

5.  Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction.

Authors:  K Murakami; W Minamide; K Wada; E Nakamura; H Teraoka; S Watanabe
Journal:  J Clin Microbiol       Date:  1991-10       Impact factor: 5.948

Review 6.  Update on clinical significance of coagulase-negative staphylococci.

Authors:  W E Kloos; T L Bannerman
Journal:  Clin Microbiol Rev       Date:  1994-01       Impact factor: 26.132

  6 in total

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