Literature DB >> 22851114

Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery.

Judson B Williams1, Eric D Peterson, J Matthew Brennan, Art Sedrakyan, Dale Tavris, John H Alexander, Renato D Lopes, Rachel S Dokholyan, Yue Zhao, Sean M O'Brien, Robert E Michler, Vinod H Thourani, Fred H Edwards, Hesha Duggirala, Thomas Gross, Danica Marinac-Dabic, Peter K Smith.   

Abstract

CONTEXT: The safety and durability of endoscopic vein graft harvest in coronary artery bypass graft (CABG) surgery has recently been called into question.
OBJECTIVE: To compare the long-term outcomes of endoscopic vs open vein-graft harvesting for Medicare patients undergoing CABG surgery in the United States. DESIGN, SETTING, AND PATIENTS: An observational study of 235,394 Medicare patients undergoing isolated CABG surgery between 2003 and 2008 at 934 surgical centers participating in the Society of Thoracic Surgeons (STS) national database. The STS records were linked to Medicare files to allow longitudinal assessment (median 3-year follow-up) through December 31, 2008. MAIN OUTCOME MEASURES: All-cause mortality. Secondary outcome measures included wound complications and the composite of death, myocardial infarction, and revascularization.
RESULTS: Based on Medicare Part B coding, 52% of patients received endoscopic vein-graft harvesting during CABG surgery. After propensity score adjustment for clinical characteristics, there were no significant differences between long-term mortality rates (13.2% [12,429 events] vs 13.4% [13,096 events]) and the composite of death, myocardial infarction, and revascularization (19.5% [18,419 events] vs 19.7% [19,232 events]). Time-to-event analysis for those patients receiving endoscopic vs open vein-graft harvesting revealed adjusted hazard ratios [HRs] of 1.00 (95% CI, 0.97-1.04) for mortality and 1.00 (95% CI, 0.98-1.05) for the composite outcome. Endoscopic vein-graft harvesting was associated with lower harvest site wound complications relative to open vein-graft harvesting (3.0% [3654/122,899 events] vs 3.6% [4047/112,495 events]; adjusted HR, 0.83; 95% CI, 0.77-0.89; P < .001).
CONCLUSION: Among patients undergoing CABG surgery, the use of endoscopic vein-graft harvesting compared with open vein-graft harvesting was not associated with increased mortality.

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Year:  2012        PMID: 22851114      PMCID: PMC3699197          DOI: 10.1001/jama.2012.8363

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  33 in total

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Authors:  Keith Allen; Davy Cheng; William Cohn; Mark Connolly; James Edgerton; Volkmar Falk; Janet Martin; Toshiya Ohtsuka; Richard Vitali
Journal:  Innovations (Phila)       Date:  2005

2.  Endoscopic saphenous vein harvesting for coronary artery bypass grafts: NICE guidance.

Authors:  James B Barnard; D J M Keenan
Journal:  Heart       Date:  2010-12-09       Impact factor: 5.994

3.  Long-term outcomes of endoscopic vein harvesting after coronary artery bypass grafting.

Authors:  Lawrence J Dacey; John H Braxton; Robert S Kramer; Joseph D Schmoker; David C Charlesworth; Robert E Helm; Carmine Frumiento; Gerald L Sardella; Robert A Clough; Stephan R Jones; David J Malenka; Elaine M Olmstead; Cathy S Ross; Gerald T O'Connor; Donald S Likosky
Journal:  Circulation       Date:  2011-01-03       Impact factor: 29.690

Review 4.  A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003.

Authors:  Peter C Austin
Journal:  Stat Med       Date:  2008-05-30       Impact factor: 2.373

5.  Corrected score estimation in the proportional hazards model with misclassified discrete covariates.

Authors:  David M Zucker; Donna Spiegelman
Journal:  Stat Med       Date:  2008-05-20       Impact factor: 2.373

Review 6.  A meta-analysis of minimally invasive versus traditional open vein harvest technique for coronary artery bypass graft surgery.

Authors:  Sheraz R Markar; Ramesh Kutty; Lyn Edmonds; Umar Sadat; Sukumaran Nair
Journal:  Interact Cardiovasc Thorac Surg       Date:  2009-11-26

7.  Assessing the sensitivity of regression results to unmeasured confounders in observational studies.

Authors:  D Y Lin; B M Psaty; R A Kronmal
Journal:  Biometrics       Date:  1998-09       Impact factor: 2.571

8.  Subcutaneous, video-assisted saphenous vein harvest: report of the first 30 cases.

Authors:  A B Lumsden; F F Eaves; J C Ofenloch; W D Jordan
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9.  Longitudinal data analysis for discrete and continuous outcomes.

Authors:  S L Zeger; K Y Liang
Journal:  Biometrics       Date:  1986-03       Impact factor: 2.571

10.  Endoscopic saphenous vein harvesting for CABG -- a randomized, prospective trial.

Authors:  U P Schurr; M L Lachat; O Reuthebuch; A Kadner; M Mäder; B Seiffert; S P Hoerstrup; G Zünd; M Genoni; M I Turina
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Review 1.  Almanac 2013: stable coronary artery disease.

Authors:  Shahed Islam; Adam Timmis
Journal:  Wien Klin Wochenschr       Date:  2013-12       Impact factor: 1.704

2.  Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV.

Authors:  Connie N Hess; Renato D Lopes; C Michael Gibson; Rebecca Hager; Daniel M Wojdyla; Brian R Englum; Michael J Mack; Robert M Califf; Nicholas T Kouchoukos; Eric D Peterson; John H Alexander
Journal:  Circulation       Date:  2014-09-26       Impact factor: 29.690

3.  Bacterial growth and wound infection following saphenous vein harvesting in cardiac surgery: a randomized controlled trial of the impact of microbial skin sealant.

Authors:  K Falk-Brynhildsen; B Söderquist; O Friberg; U Nilsson
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4.  Association of postoperative complications and outcomes following coronary artery bypass grafting.

Authors:  Oliver K Jawitz; Brian C Gulack; J Matthew Brennan; Dylan P Thibault; Alice Wang; Sean M O'Brien; Jacob N Schroder; Jeffrey G Gaca; Peter K Smith
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5.  Long-term survival after endoscopic vein harvest for coronary artery bypass grafting.

Authors:  B H Kirmani; S Power; J Zacharias
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6.  Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study.

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Review 7.  Vein graft failure: from pathophysiology to clinical outcomes.

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8.  Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery.

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9.  Response to Letters Regarding Article, "Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Insights From PREVENT IV".

Authors:  Connie N Hess; Renato D Lopes; C Michael Gibson; Rebecca Hager; Daniel M Wojdyla; Brian R Englum; Michael J Mack; Nicholas T Kouchoukos; Eric D Peterson; John H Alexander
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Review 10.  Strategies for the coronary surgeon to remain "competitive and co-operative" in the PCI era.

Authors:  George Jose Valooran; Shiv Kumar Nair; Krishnan Chandrasekharan
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