Literature DB >> 22850731

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM).

Jonathan S Ward1, Jason M Lynam, James W B Moir, David E Sanin, Adrian P Mountford, Ian J S Fairlamb.   

Abstract

A new class of photochemically-activated CO-releasing molecule (photo-CO-RM), based on a Mn(CO)(4)(C^N) system, is reported in this study. Three CO molecules are released per CO-RM molecule. Complex 3 is a fast releaser, thermally stable in the dark and a viable therapeutic agent.

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Year:  2012        PMID: 22850731     DOI: 10.1039/c2dt31588b

Source DB:  PubMed          Journal:  Dalton Trans        ISSN: 1477-9226            Impact factor:   4.390


  7 in total

1.  Electro- and Solar-Driven Fuel Synthesis with First Row Transition Metal Complexes.

Authors:  Kristian E Dalle; Julien Warnan; Jane J Leung; Bertrand Reuillard; Isabell S Karmel; Erwin Reisner
Journal:  Chem Rev       Date:  2019-02-15       Impact factor: 60.622

2.  Phototriggered cytotoxic properties of tricarbonyl manganese(I) complexes bearing α-diimine ligands towards HepG2.

Authors:  Ahmed M Mansour; Krzysztof Radacki; Rabaa M Khaled; Marwa H Soliman; Nour T Abdel-Ghani
Journal:  J Biol Inorg Chem       Date:  2021-02-27       Impact factor: 3.358

Review 3.  Carbon monoxide--physiology, detection and controlled release.

Authors:  Stefan H Heinemann; Toshinori Hoshi; Matthias Westerhausen; Alexander Schiller
Journal:  Chem Commun (Camb)       Date:  2014-04-11       Impact factor: 6.222

Review 4.  Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs).

Authors:  U Schatzschneider
Journal:  Br J Pharmacol       Date:  2014-07-02       Impact factor: 8.739

5.  Toxicity of tryptophan manganese(i) carbonyl (Trypto-CORM), against Neisseria gonorrhoeae.

Authors:  Jonathan S Ward; Rebecca Morgan; Jason M Lynam; Ian J S Fairlamb; James W B Moir
Journal:  Medchemcomm       Date:  2016-12-06       Impact factor: 3.597

Review 6.  Carbon Monoxide and Nitric Oxide as Examples of the Youngest Class of Transmitters.

Authors:  Alicja Nowaczyk; Magdalena Kowalska; Jacek Nowaczyk; Grzegorz Grześk
Journal:  Int J Mol Sci       Date:  2021-06-02       Impact factor: 5.923

7.  Manganese(I)-Catalyzed C-H Activation: The Key Role of a 7-Membered Manganacycle in H-Transfer and Reductive Elimination.

Authors:  Nasiru P Yahaya; Kate M Appleby; Magdalene Teh; Conrad Wagner; Erik Troschke; Joshua T W Bray; Simon B Duckett; L Anders Hammarback; Jonathan S Ward; Jessica Milani; Natalie E Pridmore; Adrian C Whitwood; Jason M Lynam; Ian J S Fairlamb
Journal:  Angew Chem Int Ed Engl       Date:  2016-09-07       Impact factor: 15.336

  7 in total

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