| Literature DB >> 22850208 |
Heung Jae Kim1, Woo Young Kwak, Jong Pil Min, Si Young Sung, Ha Dong Kim, Mi Kyung Kim, Hae Sun Kim, Kyung Jin Park, Moon Ho Son, Soon Hoe Kim, Bong Jin Lee.
Abstract
Inhibitors of dipeptidyl peptidase-4 (DPP4) have been shown to be effective treatments for type 2 diabetes. Several series of β-amino amide containing piperazine derivatives have been prepared and evaluated as a inhibitor of DPP4. Finally compound 5m was selected for further evaluation.Entities:
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Year: 2012 PMID： 22850208 DOI： 10.1016/j.bmcl.2012.07.019
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823