Literature DB >> 22846717

Heavy cervical cancer burden in elderly women: how can we improve the situation?

Malgorzata E Skaznik-Wikiel1, Paniti Sukumvanich, R Marshall Austin, Kristin K Zorn, Thomas C Krivak, Robert P Edwards, Alexander B Olawaiye.   

Abstract

OBJECTIVES: The American Cancer Society, the American College of Obstetricians and Gynecologists and the US Preventive Services Task Force recommend discontinuation of cervical cancer screening between 65 and 70 years of age in women with no abnormal test results in the preceding 10 years. This population-based study was undertaken to determine the incidence of cervical cancer in different age groups as a means to establish if current screening recommendations need reevaluation. STUDY
DESIGN: Data from the SEER database were used to compute incidence rates for cervical cancer diagnosed between 2000 and 2006 by age and disease stage.
RESULTS: We identified 18,003 women with cervical cancer. 12.18% were above the age of 69. The incidence in this age group was 8.7/100,000. Women younger than 30 comprised 5.7% of patients with an incidence of 5/100,000 and were most commonly diagnosed with stage IA1 disease. Women above 70 were most frequently diagnosed with stage IIIB. 79% of patients younger than 30 were diagnosed with an early disease (stage IA1-IIA) as opposed to only 41.2% of patients aged 69 or above.
CONCLUSIONS: The incidence of cervical cancer does not decrease significantly in older women. Women over the age of 70 are frequently diagnosed with advanced stage disease which limits their treatment options. Failure to apply uniform screening across all at-risk age groups may account for the discrepancy.
Copyright © 2012 S. Karger AG, Basel.

Entities:  

Mesh:

Year:  2012        PMID: 22846717     DOI: 10.1159/000338555

Source DB:  PubMed          Journal:  Acta Cytol        ISSN: 0001-5547            Impact factor:   2.319


  7 in total

1.  [Evaluation of mortality after the analysis of the screening history in women diagnosed with infiltrating cervical cancer].

Authors:  Marta Castillo; Aurora Astudillo; Omar Clavero; Julio Velasco; Raquel Ibáñez; Silvia de Sanjosé
Journal:  Aten Primaria       Date:  2017-06-16       Impact factor: 1.137

2.  Construction, Validation, and Visualization of Two Web-Based Nomograms for Predicting Overall Survival and Cancer-Specific Survival in Elderly Patients with Primary Osseous Spinal Neoplasms.

Authors:  Yuexin Tong; Yuekai Cui; Liming Jiang; Yuan Zeng; Dongxu Zhao
Journal:  J Oncol       Date:  2022-04-04       Impact factor: 4.375

3.  Distribution of HPV Genotypes and Involvement of Risk Factors in Cervical Lesions and Invasive Cervical Cancer: A Study in an Indian Population.

Authors:  Shikha Srivastava; U P Shahi; Arti Dibya; Sadhana Gupta; Jagat K Roy
Journal:  Int J Mol Cell Med       Date:  2014

4.  Poor Cervical Cancer Screening Attendance and False Negatives. A Call for Organized Screening.

Authors:  Marta Castillo; Aurora Astudillo; Omar Clavero; Julio Velasco; Raquel Ibáñez; Silvia de Sanjosé
Journal:  PLoS One       Date:  2016-08-22       Impact factor: 3.240

5.  Outcome and toxicity of radical radiotherapy or concurrent Chemoradiotherapy for elderly cervical cancer women.

Authors:  Weiping Wang; Xiaorong Hou; Junfang Yan; Jie Shen; Xin Lian; Shuai Sun; Zhikai Liu; Qingyu Meng; Dunhuang Wang; Mei Zhao; Jie Qiu; Ke Hu; Fuquan Zhang
Journal:  BMC Cancer       Date:  2017-08-01       Impact factor: 4.430

6.  Cervical Cancer Among Older Women: Analyses of Surveillance, Epidemiology and End Results Program Data.

Authors:  Allison M Quick; Jessica L Krok-Schoen; Julie A Stephens; James L Fisher
Journal:  Cancer Control       Date:  2020 Jan-Dec       Impact factor: 3.302

7.  Prognostic Model for Predicting Overall and Cancer-Specific Survival Among Patients With Cervical Squamous Cell Carcinoma: A SEER Based Study.

Authors:  Zhuolin Li; Yao Lin; Bizhen Cheng; Qiaoxin Zhang; Yingmu Cai
Journal:  Front Oncol       Date:  2021-07-14       Impact factor: 6.244

  7 in total

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