| Literature DB >> 22846372 |
A Christy Hunter1, Jacqueline Elsom, Peter P Wibroe, S Moein Moghimi.
Abstract
The oral route for delivery of pharmaceuticals is the most widely used and accepted. Nanoparticles and microparticles are increasingly being applied within this arena to optimize drug targeting and bioavailability. Frequently the carrier systems used are either constructed from or contain polymeric materials. Examples of these nanocarriers include polymeric nanoparticles, solid lipid nanocarriers, self-nanoemulsifying drug delivery systems and nanocrystals. It is the purpose of this review to describe these cutting edge technologies and specifically focus on the interaction and fate of these polymers within the gastrointestinal system.Entities:
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Year: 2012 PMID: 22846372 DOI: 10.1016/j.nano.2012.07.005
Source DB: PubMed Journal: Nanomedicine ISSN: 1549-9634 Impact factor: 5.307