Literature DB >> 22846372

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective.

A Christy Hunter1, Jacqueline Elsom, Peter P Wibroe, S Moein Moghimi.   

Abstract

The oral route for delivery of pharmaceuticals is the most widely used and accepted. Nanoparticles and microparticles are increasingly being applied within this arena to optimize drug targeting and bioavailability. Frequently the carrier systems used are either constructed from or contain polymeric materials. Examples of these nanocarriers include polymeric nanoparticles, solid lipid nanocarriers, self-nanoemulsifying drug delivery systems and nanocrystals. It is the purpose of this review to describe these cutting edge technologies and specifically focus on the interaction and fate of these polymers within the gastrointestinal system.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22846372     DOI: 10.1016/j.nano.2012.07.005

Source DB:  PubMed          Journal:  Nanomedicine        ISSN: 1549-9634            Impact factor:   5.307


  14 in total

1.  Consideration of the efficacy of non-ionic vesicles in the targeted delivery of oral vaccines.

Authors:  Jitinder S Wilkhu; Sarah E McNeil; David E Anderson; Yvonne Perrie
Journal:  Drug Deliv Transl Res       Date:  2014-06       Impact factor: 4.617

Review 2.  From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity.

Authors:  Natalie L Trevaskis; Lisa M Kaminskas; Christopher J H Porter
Journal:  Nat Rev Drug Discov       Date:  2015-10-16       Impact factor: 84.694

Review 3.  Nanoparticles for oral delivery: Design, evaluation and state-of-the-art.

Authors:  Abhijit A Date; Justin Hanes; Laura M Ensign
Journal:  J Control Release       Date:  2016-06-09       Impact factor: 9.776

4.  Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse.

Authors:  Katharina Maisel; Laura Ensign; Mihika Reddy; Richard Cone; Justin Hanes
Journal:  J Control Release       Date:  2014-11-04       Impact factor: 9.776

5.  A trial for the design and optimization of pH-sensitive microparticles for intestinal delivery of cinnarizine.

Authors:  Hussein O Ammar; Mahmoud Ghorab; Rabab Kamel; Alaa H Salama
Journal:  Drug Deliv Transl Res       Date:  2016-06       Impact factor: 4.617

Review 6.  Planar bioadhesive microdevices: a new technology for oral drug delivery.

Authors:  Cade B Fox; Hariharasudhan D Chirra; Tejal A Desai
Journal:  Curr Pharm Biotechnol       Date:  2014       Impact factor: 2.837

Review 7.  Micro/nanofabricated platforms for oral drug delivery.

Authors:  Cade B Fox; Jean Kim; Long V Le; Cameron L Nemeth; Hariharasudhan D Chirra; Tejal A Desai
Journal:  J Control Release       Date:  2015-08-02       Impact factor: 9.776

8.  Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers.

Authors:  Jacob S Brenner; Samir Mitragotri; Vladimir R Muzykantov
Journal:  Annu Rev Biomed Eng       Date:  2021-03-31       Impact factor: 11.324

9.  Nanoparticle patterning for biomedicine.

Authors:  Seyed Moein Moghimi
Journal:  Bioimpacts       Date:  2016-12-28

10.  Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice.

Authors:  Maria Talita Pacheco de Oliveira; Diego de Sá Coutinho; Sílvia Stanisçuaski Guterres; Adriana Raffin Pohlmann; Patrícia Machado Rodrigues E Silva; Marco Aurélio Martins; Andressa Bernardi
Journal:  Pharmaceutics       Date:  2021-05-10       Impact factor: 6.321

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