BACKGROUND: The safety of the blood supply is ensured through several procedures from donor selection to testing of donated units. Examination of the donor deferrals at different centers provides insights into the role that deferrals play in transfusion safety. STUDY DESIGN AND METHODS: A cross-sectional descriptive study of prospective allogeneic blood donors at three large blood centers located in São Paulo, Belo Horizonte, and Recife, Brazil, from August 2007 to December 2009 was conducted. Deferrals were grouped into similar categories across the centers, and within each center frequencies out of all presentations were determined. RESULTS: Of 963,519 prospective blood donors at the three centers, 746,653 (77.5%) were accepted and 216,866 (22.5%) were deferred. Belo Horizonte had the highest overall deferral proportion of 27%, followed by Recife (23%) and São Paulo (19%). Females were more likely to be deferred than males (30% vs. 18%, respectively). The three most common deferral reasons were low hematocrit or hemoglobin, medical diagnoses, and higher-risk behavior. CONCLUSION: The types and frequencies of deferral vary substantially among the three blood centers. Factors that may explain the differences include demographic characteristics, the order in which health history and vital signs are taken, the staff training, and the way deferrals are coded by the centers among other policies. The results indicate that blood donor deferral in Brazil has regional aspects that should be considered when national policies are developed.
BACKGROUND: The safety of the blood supply is ensured through several procedures from donor selection to testing of donated units. Examination of the donor deferrals at different centers provides insights into the role that deferrals play in transfusion safety. STUDY DESIGN AND METHODS: A cross-sectional descriptive study of prospective allogeneic blood donors at three large blood centers located in São Paulo, Belo Horizonte, and Recife, Brazil, from August 2007 to December 2009 was conducted. Deferrals were grouped into similar categories across the centers, and within each center frequencies out of all presentations were determined. RESULTS: Of 963,519 prospective blood donors at the three centers, 746,653 (77.5%) were accepted and 216,866 (22.5%) were deferred. Belo Horizonte had the highest overall deferral proportion of 27%, followed by Recife (23%) and São Paulo (19%). Females were more likely to be deferred than males (30% vs. 18%, respectively). The three most common deferral reasons were low hematocrit or hemoglobin, medical diagnoses, and higher-risk behavior. CONCLUSION: The types and frequencies of deferral vary substantially among the three blood centers. Factors that may explain the differences include demographic characteristics, the order in which health history and vital signs are taken, the staff training, and the way deferrals are coded by the centers among other policies. The results indicate that blood donor deferral in Brazil has regional aspects that should be considered when national policies are developed.
Authors: Ester C Sabino; Thelma T Gonçalez; Anna Bárbara Carneiro-Proietti; Moussa Sarr; João Eduardo Ferreira; Divaldo A Sampaio; Nanci A Salles; David J Wright; Brian Custer; Michael Busch Journal: Transfusion Date: 2011-10-07 Impact factor: 3.157
Authors: Claudia C Barreto; Ester C Sabino; Thelma T Gonçalez; Megan E Laycock; Brandee L Pappalardo; Nanci A Salles; David J Wright; Dalton F Chamone; Michael P Busch Journal: Transfusion Date: 2005-11 Impact factor: 3.157
Authors: Alan E Mast; Karen S Schlumpf; David J Wright; Brian Custer; Bryan Spencer; Edward L Murphy; Toby L Simon Journal: Transfusion Date: 2010-04-15 Impact factor: 3.157
Authors: Cláudia Di Lorenzo Oliveira; Flávia Loureiro; Maria R D de Bastos; Fernando A Proietti; Anna B F Carneiro-Proietti Journal: Transfusion Date: 2009-01-02 Impact factor: 3.157
Authors: Shimian Zou; Fatemeh Musavi; Edward P Notari; Jorge A Rios; Jonathan Trouern-Trend; Chyang T Fang Journal: Transfusion Date: 2008-08-20 Impact factor: 3.157
Authors: Giuseppina Maria Patavino; Cesar de Almeida-Neto; Jing Liu; David J Wright; Alfredo Mendrone-Junior; Maria Inês Lopes Ferreira; Anna Bárbara de Freitas Carneiro; Brian Custer; João Eduardo Ferreira; Michael P Busch; Ester Cerdeira Sabino Journal: Transfusion Date: 2011-07-14 Impact factor: 3.157
Authors: C Miranda; E Moreno; R Bruhn; N M Larsen; D J Wright; C D L Oliveira; A B F Carneiro-Proietti; P Loureiro; C de Almeida-Neto; B Custer; E C Sabino; T T Gonçalez Journal: Vox Sang Date: 2013-12-09 Impact factor: 2.144
Authors: Paula Loureiro; Cesar de Almeida-Neto; Anna Bárbara Carneiro Proietti; Ligia Capuani; Thelma Terezinha Gonçalez; Claudia Di Lorenzo de Oliveira; Silvana Carneiro Leão; Maria Inês Lopes; Divaldo Sampaio; Giuseppina Maria Patavino; João Eduardo Ferreira; Paula Fraiman Blatyta; Maria Esther Duarte Lopes; Alfredo Mendrone-Junior; Nanci Alves Salles; Melissa King; Edward Murphy; Michael Busch; Brian Custer; Ester Cerdeira Sabino Journal: Rev Bras Hematol Hemoter Date: 2014-03