OBJECTIVES: Infectious diseases, even vaccine preventable ones, might affect transplanting and the life course in pediatric solid-organ recipients. Owing to immunosuppression and decreased antibody production, susceptibility to infections is increased in these patients. MATERIALS AND METHODS: The present study was designed to assess the vaccination and antibody status of the pediatric renal transplant patients. Fifty-one patients who were admitted to the regional transplant center for renal transplant were retrospectively evaluated. Patient 's vaccination charts were examined, and their immunization status was determined by antibody titers against hepatitis B, hepatitis A, measles, mumps, rubella, and varicella. RESULTS: The study group was composed of 23 males and 28 females (mean age, 10.8 y; age range, 2-17 y). All patients ' vaccination status was appropriate with their ages according to national vaccination program. Antibodies were positive for hepatitis B in 84.3% patients, 76.5% for hepatitis A, 72.5% for measles, 64.7% for mumps, 64.7% for rubella, and 72.5% for varicella. CONCLUSIONS: Seronegativity for common childhood diseases may complicate the posttransplant period owing to increased risk of infections. Especially in developing countries, immunization protocols and vaccination program schedules should be reviewed before transplant to prevent serious complications caused by these diseases.
OBJECTIVES: Infectious diseases, even vaccine preventable ones, might affect transplanting and the life course in pediatric solid-organ recipients. Owing to immunosuppression and decreased antibody production, susceptibility to infections is increased in these patients. MATERIALS AND METHODS: The present study was designed to assess the vaccination and antibody status of the pediatric renal transplant patients. Fifty-one patients who were admitted to the regional transplant center for renal transplant were retrospectively evaluated. Patient 's vaccination charts were examined, and their immunization status was determined by antibody titers against hepatitis B, hepatitis A, measles, mumps, rubella, and varicella. RESULTS: The study group was composed of 23 males and 28 females (mean age, 10.8 y; age range, 2-17 y). All patients ' vaccination status was appropriate with their ages according to national vaccination program. Antibodies were positive for hepatitis B in 84.3% patients, 76.5% for hepatitis A, 72.5% for measles, 64.7% for mumps, 64.7% for rubella, and 72.5% for varicella. CONCLUSIONS: Seronegativity for common childhood diseases may complicate the posttransplant period owing to increased risk of infections. Especially in developing countries, immunization protocols and vaccination program schedules should be reviewed before transplant to prevent serious complications caused by these diseases.
Authors: Britta Höcker; Martin Aguilar; Paul Schnitzler; Lars Pape; Martin Bald; Jens König; Stephen D Marks; Gurkan Genc; Anja Büscher; Markus J Kemper; Heiko Billing; Martin Pohl; Luca Dello Strologo; Nicholas J A Webb; Susanne Rieger; Annette Mankertz; Kai Krupka; Thomas Bruckner; Alexander Fichtner; Burkhard Tönshoff Journal: Pediatr Nephrol Date: 2018-01-10 Impact factor: 3.714
Authors: Britta Höcker; Martin Aguilar; Paul Schnitzler; Lars Pape; Luca Dello Strologo; Nicholas J A Webb; Martin Bald; Gurkan Genc; Heiko Billing; Jens König; Anja Büscher; Markus J Kemper; Stephen D Marks; Martin Pohl; Marianne Wigger; Rezan Topaloglu; Susanne Rieger; Kai Krupka; Thomas Bruckner; Alexander Fichtner; Burkhard Tönshoff Journal: Pediatr Nephrol Date: 2017-10-05 Impact factor: 3.714