Literature DB >> 22845493

The ubiquity of iron.

Perry A Frey1, George H Reed.   

Abstract

The importance of iron in living systems can be traced to the many complexes within which it is found, to its chemical mobility in undergoing oxidation-reduction reactions, and to the abundance of iron in Earth's crust. Iron is the most abundant element, by mass, in the Earth, constituting about 80% of the inner and outer cores of Earth. The molten outer core is about 8000 km in diameter, and the solid inner core is about 2400 km in diameter. Iron is the fourth most abundant element in Earth's crust. It is the chemically functional component of mononuclear iron complexes, dinuclear iron complexes, [2Fe-2S] and [4Fe-4S] clusters, [Fe-Ni-S] clusters, iron protophorphyrin IX, and many other complexes in protein biochemistry. Metals such as nickel, cobalt, copper, and manganese are present in the crust and could in principle function chemically in place of iron, but they are scarce in Earth's crust. Iron is plentiful because of its nuclear stability in stellar nuclear fusion reactions. It seems likely that other solid planets, formed by the same processes as Earth, would also foster the evolution of life and that iron would be similarly important to life on those planets as it is on Earth.

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Year:  2012        PMID: 22845493     DOI: 10.1021/cb300323q

Source DB:  PubMed          Journal:  ACS Chem Biol        ISSN: 1554-8929            Impact factor:   5.100


  35 in total

1.  Structure and Metal Binding Properties of Chlamydia trachomatis YtgA.

Authors:  Zhenyao Luo; Stephanie L Neville; Rebecca Campbell; Jacqueline R Morey; Shruti Menon; Mark Thomas; Bart A Eijkelkamp; Miranda P Ween; Wilhelmina M Huston; Bostjan Kobe; Christopher A McDevitt
Journal:  J Bacteriol       Date:  2019-12-06       Impact factor: 3.490

Review 2.  Genetic engineered molecular imaging probes for applications in cell therapy: emphasis on MRI approach.

Authors:  In K Cho; Silun Wang; Hui Mao; Anthony Ws Chan
Journal:  Am J Nucl Med Mol Imaging       Date:  2016-09-22

3.  Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection.

Authors:  Laura A Mike; Sara N Smith; Christopher A Sumner; Kathryn A Eaton; Harry L T Mobley
Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-07       Impact factor: 11.205

4.  Dexmedetomidine Promotes SH-SY5Y Cell Resistance Against Impairment of Iron Overload by Inhibiting NF-κB Pathways.

Authors:  Xi-Bei Hu; Zhi-Yu Xi; Lin-Qing Liu; Kai Kang; Wan-Hong Li; Yu-Xian Shen; Fang Kang; Juan Li
Journal:  Neurochem Res       Date:  2019-01-29       Impact factor: 3.996

5.  Human calprotectin affects the redox speciation of iron.

Authors:  Toshiki G Nakashige; Elizabeth M Nolan
Journal:  Metallomics       Date:  2017-08-16       Impact factor: 4.526

Review 6.  The role of iron homeostasis and iron-mediated ROS in cancer.

Authors:  Jia-Fu Ying; Ze-Bei Lu; Luo-Qin Fu; Yu Tong; Zhen Wang; Wei-Fen Li; Xiao-Zhou Mou
Journal:  Am J Cancer Res       Date:  2021-05-15       Impact factor: 6.166

7.  Iron Homeostasis and Metabolism: Two Sides of a Coin.

Authors:  Vivek Venkataramani
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 8.  The role of iron and reactive oxygen species in cell death.

Authors:  Scott J Dixon; Brent R Stockwell
Journal:  Nat Chem Biol       Date:  2014-01       Impact factor: 15.040

9.  Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells.

Authors:  James D Vasta; Kristen A Andersen; Kathryn M Deck; Christopher P Nizzi; Richard S Eisenstein; Ronald T Raines
Journal:  ACS Chem Biol       Date:  2015-11-19       Impact factor: 5.100

10.  Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis.

Authors:  Jarred W Rensvold; Kimberly A Krautkramer; James A Dowell; John M Denu; David J Pagliarini
Journal:  J Biol Chem       Date:  2016-08-05       Impact factor: 5.157

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