BACKGROUND: Alcohol, exercise or non-steroidal anti-inflamatory drugs (NSAID) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published. METHODS: Descriptive study including 74 cases of suspected co-factor enhanced food allergy, assessed by skin-prick tests, specific IgE and oral challenges. RESULTS: Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant-derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen. CONCLUSIONS: Co-factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.
BACKGROUND:Alcohol, exercise or non-steroidal anti-inflamatory drugs (NSAID) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published. METHODS: Descriptive study including 74 cases of suspected co-factor enhanced food allergy, assessed by skin-prick tests, specific IgE and oral challenges. RESULTS: Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant-derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen. CONCLUSIONS: Co-factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.
Authors: Rosa Muñoz-Cano; Mariona Pascal; Joan Bartra; Cesar Picado; Antonio Valero; Do-Kyun Kim; Stephen Brooks; Michael Ombrello; Dean D Metcalfe; Juan Rivera; Ana Olivera Journal: J Allergy Clin Immunol Date: 2015-07-17 Impact factor: 10.793
Authors: Luis Caraballo; Josefina Zakzuk; Bee Wah Lee; Nathalie Acevedo; Jian Yi Soh; Mario Sánchez-Borges; Elham Hossny; Elizabeth García; Nelson Rosario; Ignacio Ansotegui; Leonardo Puerta; Jorge Sánchez; Victoria Cardona Journal: World Allergy Organ J Date: 2016-06-27 Impact factor: 4.084
Authors: Astrid Versluis; Harmieke van Os-Medendorp; Astrid G Kruizinga; W Marty Blom; Geert F Houben; André C Knulst Journal: Immun Inflamm Dis Date: 2016-09-15
Authors: Rosa Muñoz-Cano; Mariona Pascal; Giovanna Araujo; M J Goikoetxea; Antonio L Valero; Cesar Picado; Joan Bartra Journal: Front Immunol Date: 2017-09-26 Impact factor: 7.561