Literature DB >> 22844549

Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature.

Shweta Kurian1, Jessica Macintyre, Muzammil Mushtaq, Caio Max Rocha-Lima, Yeon Ahn.   

Abstract

Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.

Entities:  

Keywords:  Disseminated intravascular coagulation; Hematological emergencies; Metastatic colon cancer; Oxaliplatin; Platelet count

Year:  2012        PMID： 22844549      PMCID： PMC3406283          DOI： 10.4251/wjgo.v4.i7.181

Source DB:  PubMed          Journal:  World J Gastrointest Oncol


  19 in total

1.  Oxaliplatin-induced haematological emergency with an immediate severe thrombocytopenia and haemolysis.

Authors:  H Sørbye; Y Bruserud; O Dahl
Journal:  Acta Oncol       Date:  2001       Impact factor: 4.089

2.  Oxaliplatin-induced immune thrombocytopenia.

Authors:  Michel Pavic; Pierre Moncharmont; Pascal Sève; Dominique Rigal; Christiane Broussolle
Journal:  Gastroenterol Clin Biol       Date:  2006-05

3.  Life-threatening oxaliplatin-induced acute thrombocytopenia, hemolysis and bleeding: a case report.

Authors:  Michele Santodirocco; Valentina Lombardi; Cinzia Fesce; Gaetano Palumbo; Silvana Capalbo; Matteo Landriscina
Journal:  Acta Oncol       Date:  2008       Impact factor: 4.089

4.  Oxaliplatin-induced fever and release of IL-6.

Authors:  H Ulrich-Pur; M Penz; W C Fiebiger; B Schüll; G V Kornek; W Scheithauer; M Raderer
Journal:  Oncology       Date:  2000-09       Impact factor: 2.935

5.  Oxaliplatin-induced haemolytic anaemia.

Authors:  J Desrame; H Broustet; P Darodes de Tailly; D Girard; J M Saissy
Journal:  Lancet       Date:  1999-10-02       Impact factor: 79.321

6.  Oxaliplatin-induced immune mediated thrombocytopenia.

Authors:  Muhammad S Beg; Rami S Komrokji; Kashif Ahmed; Malek M Safa
Journal:  Cancer Chemother Pharmacol       Date:  2008-01-19       Impact factor: 3.333

7.  A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

Authors:  Richard M Goldberg; Daniel J Sargent; Roscoe F Morton; Charles S Fuchs; Ramesh K Ramanathan; Stephen K Williamson; Brian P Findlay; Henry C Pitot; Steven R Alberts
Journal:  J Clin Oncol       Date:  2003-12-09       Impact factor: 44.544

8.  Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.

Authors:  Thierry André; Corrado Boni; Lamia Mounedji-Boudiaf; Matilde Navarro; Josep Tabernero; Tamas Hickish; Clare Topham; Marta Zaninelli; Philip Clingan; John Bridgewater; Isabelle Tabah-Fisch; Aimery de Gramont
Journal:  N Engl J Med       Date:  2004-06-03       Impact factor: 91.245

9.  Fatal thrombocytopenia after oxaliplatin-based chemotherapy.

Authors:  Yu-Yun Shao; Ruey-Long Hong
Journal:  Anticancer Res       Date:  2008 Sep-Oct       Impact factor: 2.480

10.  Oxaliplatin-induced Evan's syndrome.

Authors:  C C Earle; W Y Chen; D P Ryan; R J Mayer
Journal:  Br J Cancer       Date:  2001-02-02       Impact factor: 7.640
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