Literature DB >> 2284218

Clinical pharmacokinetic studies with lornoxicam.

P Turner1, A Johnston.   

Abstract

Pharmacokinetic data from several studies in young and elderly human subjects are reviewed. Lornoxicam appears to be extensively metabolized and no unchanged drug has been found in the urine. It has a relatively short elimination half-life (about 4 hours), and no significant differences in pharmacokinetic data have been found between young and elderly volunteers.

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Year:  1990        PMID: 2284218

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  7 in total

1.  Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam.

Authors:  P Bonnabry; T Leemann; P Dayer
Journal:  Eur J Clin Pharmacol       Date:  1996       Impact factor: 2.953

Review 2.  Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions.

Authors:  J A Balfour; A Fitton; L B Barradell
Journal:  Drugs       Date:  1996-04       Impact factor: 9.546

3.  Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype.

Authors:  Yifan Zhang; Dafang Zhong; Dayong Si; Yingjie Guo; Xiaoyan Chen; Hui Zhou
Journal:  Br J Clin Pharmacol       Date:  2005-01       Impact factor: 4.335

4.  A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam.

Authors:  M Ravic; I Salas-Herrera; A Johnston; P Turner; K Foley; D E Rosenow
Journal:  Postgrad Med J       Date:  1993-11       Impact factor: 2.401

Review 5.  Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents.

Authors:  K T Olkkola; A V Brunetto; M J Mattila
Journal:  Clin Pharmacokinet       Date:  1994-02       Impact factor: 6.447

Review 6.  Clinical pharmacokinetics of lornoxicam. A short half-life oxicam.

Authors:  N M Skjodt; N M Davies
Journal:  Clin Pharmacokinet       Date:  1998-06       Impact factor: 6.447

7.  Aqueous Ginger (Zingiber officinale) Extract Ameliorates the Harmful Effects of High-Dose Lornoxicam in Albino Male Rats.

Authors:  Sabry M El-Bahr; Rabab R Elzoghby; Mohammed A Alfattah; Mahmoud Kandeel; Ahlam F Hamouda
Journal:  Biomed Res Int       Date:  2022-08-02       Impact factor: 3.246

  7 in total

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