Literature DB >> 22841716

Towards an artificial cell.

Daniel A Hammer1, Neha P Kamat.   

Abstract

We are on the verge of producing "synthetic cells," or protocells, in which some, many or all of the tasks of a real biological cell are harnessed into a synthetic platform. Such advances are made possible through genetic engineering, microfabrication technologies, and the development of cellular membranes from new surfactants that extend beyond phospholipids in stability and chemical control, and can be used to introduce designer functionality into membranes and cells. We review some of the recent advances in the development of synthetic cells and suggest future exciting directions.
Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22841716     DOI: 10.1016/j.febslet.2012.07.044

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  19 in total

1.  Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation.

Authors:  Sean Allen; Omar Osorio; Yu-Gang Liu; Evan Scott
Journal:  J Control Release       Date:  2017-07-20       Impact factor: 9.776

2.  Microfluidic generation of PEG-b-PLA polymersomes containing alginate-based core hydrogel.

Authors:  Chiara Martino; Tae Yong Lee; Shin-Hyun Kim; Andrew J deMello
Journal:  Biomicrofluidics       Date:  2015-03-03       Impact factor: 2.800

3.  Liquid-liquid phase separation in artificial cells.

Authors:  Charles D Crowe; Christine D Keating
Journal:  Interface Focus       Date:  2018-08-17       Impact factor: 3.906

4.  Membrane remodelling by a lipidated endosomal sorting complex required for transport-III chimera, in vitro.

Authors:  C J Marklew; A Booth; P A Beales; B Ciani
Journal:  Interface Focus       Date:  2018-08-17       Impact factor: 3.906

Review 5.  Droplet-based microfluidics for artificial cell generation: a brief review.

Authors:  Chiara Martino; Andrew J deMello
Journal:  Interface Focus       Date:  2016-08-06       Impact factor: 3.906

Review 6.  Glycan-decorated protocells: novel features for rebuilding cellular processes.

Authors:  Ramin Omidvar; Winfried Römer
Journal:  Interface Focus       Date:  2019-02-15       Impact factor: 3.906

7.  Self-assembling cages from coiled-coil peptide modules.

Authors:  Jordan M Fletcher; Robert L Harniman; Frederick R H Barnes; Aimee L Boyle; Andrew Collins; Judith Mantell; Thomas H Sharp; Massimo Antognozzi; Paula J Booth; Noah Linden; Mervyn J Miles; Richard B Sessions; Paul Verkade; Derek N Woolfson
Journal:  Science       Date:  2013-04-11       Impact factor: 47.728

Review 8.  Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine.

Authors:  Jie Sun; Eric Jakobsson; Yingxiao Wang; C Jeffrey Brinker
Journal:  Life (Basel)       Date:  2015-01-19

Review 9.  Synthetic Biology: A Bridge between Artificial and Natural Cells.

Authors:  Yunfeng Ding; Fan Wu; Cheemeng Tan
Journal:  Life (Basel)       Date:  2014-12-19

Review 10.  Developments in the tools and methodologies of synthetic biology.

Authors:  Richard Kelwick; James T MacDonald; Alexander J Webb; Paul Freemont
Journal:  Front Bioeng Biotechnol       Date:  2014-11-26
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