| Literature DB >> 22841347 |
Katja G Weinacht1, Patrick M Brauer, Kerstin Felgentreff, Alex Devine, Andrew R Gennery, Silvia Giliani, Waleed Al-Herz, Axel Schambach, Juan Carlos Zúñiga-Pflücker, Luigi D Notarangelo.
Abstract
The advent of reprogramming technology has greatly advanced the field of stem cell biology and nurtured our hope to create patient specific renewable stem cell sources. While the number of reports of disease specific induced pluripotent stem cells is continuously rising, the field becomes increasingly more aware that induced pluripotent stem cells are not as similar to embryonic stem cells as initially assumed. Our state of the art understanding of human induced pluripotent stem cells, their capacity, their limitations and their promise as it pertains to the study and treatment of primary immunodeficiencies, is the content of this review.Entities:
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Year: 2012 PMID: 22841347 PMCID: PMC3478496 DOI: 10.1016/j.coi.2012.07.001
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486