BACKGROUND: Sleep-disordered breathing (SDB) is an increasingly recognized risk factor for cardiovascular disease (CVD). Limited data are available from large African American cohorts. METHODS: We examined the prevalence, burden, and correlates of sleep symptoms suggestive of SDB and risk for obstructive sleep apnea (OSA) in the Jackson Heart Study (JHS), an all-African-American cohort of 5301 adults. Data on selected daytime and nighttime sleep symptoms were collected using a modified Berlin questionnaire during the baseline examination. Risk of OSA was calculated according to published prediction model. Age and multivariable-adjusted logistic regression models were used to examine the associations between potential risk factors and measures of sleep. RESULTS: Sleep symptoms, burden, and risk of OSA were high among men and women in the JHS and increased with age and obesity. Being married was positively associated with sleep symptoms among women. In men, poor to fair perceived health and increased levels of stress were associated with higher odds of sleep burden, whereas prevalent hypertension and CVD were associated with higher odds of OSA risk. Similar associations were observed among women with slight variations. Sleep duration <7h was associated with increased odds of sleep symptoms among women and increased sleep burden among men. Moderate to severe restless sleep was consistently and positively associated with odds of adverse sleep symptoms, sleep burden, and high risk OSA. CONCLUSIONS: Sleep symptoms in JHS had a strong positive association with features of visceral obesity, stress, and poor perceived health. With increasing obesity among younger African Americans, these findings are likely to have broad public health implications.
BACKGROUND:Sleep-disordered breathing (SDB) is an increasingly recognized risk factor for cardiovascular disease (CVD). Limited data are available from large African American cohorts. METHODS: We examined the prevalence, burden, and correlates of sleep symptoms suggestive of SDB and risk for obstructive sleep apnea (OSA) in the Jackson Heart Study (JHS), an all-African-American cohort of 5301 adults. Data on selected daytime and nighttime sleep symptoms were collected using a modified Berlin questionnaire during the baseline examination. Risk of OSA was calculated according to published prediction model. Age and multivariable-adjusted logistic regression models were used to examine the associations between potential risk factors and measures of sleep. RESULTS:Sleep symptoms, burden, and risk of OSA were high among men and women in the JHS and increased with age and obesity. Being married was positively associated with sleep symptoms among women. In men, poor to fair perceived health and increased levels of stress were associated with higher odds of sleep burden, whereas prevalent hypertension and CVD were associated with higher odds of OSA risk. Similar associations were observed among women with slight variations. Sleep duration <7h was associated with increased odds of sleep symptoms among women and increased sleep burden among men. Moderate to severe restless sleep was consistently and positively associated with odds of adverse sleep symptoms, sleep burden, and high risk OSA. CONCLUSIONS:Sleep symptoms in JHS had a strong positive association with features of visceral obesity, stress, and poor perceived health. With increasing obesity among younger African Americans, these findings are likely to have broad public health implications.
Authors: James G Wilson; Charles N Rotimi; Lynette Ekunwe; Charmaine D M Royal; Mary E Crump; Sharon B Wyatt; Michael W Steffes; Adebowale Adeyemo; Jie Zhou; Herman A Taylor; Cashell Jaquish Journal: Ethn Dis Date: 2005 Impact factor: 1.847
Authors: Cynthia L Ogden; Margaret D Carroll; Lester R Curtin; Margaret A McDowell; Carolyn J Tabak; Katherine M Flegal Journal: JAMA Date: 2006-04-05 Impact factor: 56.272
Authors: Patricia M Dubbert; Teresa Carithers; Barbara E Ainsworth; Herman A Taylor; Gregory Wilson; Sharon B Wyatt Journal: Ethn Dis Date: 2005 Impact factor: 1.847
Authors: Thomas J Payne; Sharon B Wyatt; Thomas H Mosley; Patricia M Dubbert; Mary Lou Guiterrez-Mohammed; Rosie L Calvin; Herman A Taylor; David R Williams Journal: Ethn Dis Date: 2005 Impact factor: 1.847
Authors: Raouf Amin; Leonard Anthony; Virend Somers; Matthew Fenchel; Keith McConnell; Jenny Jefferies; Paul Willging; Maninder Kalra; Stephen Daniels Journal: Am J Respir Crit Care Med Date: 2008-01-03 Impact factor: 21.405
Authors: Massimiliano M Siccoli; Justin C T Pepperell; Malcolm Kohler; Sonya E Craig; Robert J O Davies; John R Stradling Journal: Sleep Date: 2008-11 Impact factor: 5.849
Authors: Alberto R Ramos; Douglas M Wallace; Seithikurippu Ratnas Pandi-Perumal; Natasha J Williams; Chimene Castor; Mary Ann Sevick; Samy I Mcfarlane; Girardin Jean-Louis Journal: Ann Med Date: 2015-04-09 Impact factor: 4.709
Authors: Joshua J Joseph; Justin B Echouffo-Tcheugui; Sameera A Talegawkar; Valery S Effoe; Victoria Okhomina; Mercedes R Carnethon; Willa A Hsueh; Sherita H Golden Journal: Am J Prev Med Date: 2017-08-14 Impact factor: 5.043