Literature DB >> 22840451

Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice.

S Rajan1, H Suganya, T Thirunalasundari, S Jeeva.   

Abstract

OBJECTIVE: To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.
METHODS: Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.
RESULTS: Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.
CONCLUSIONS: The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.
Copyright © 2012 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 22840451     DOI: 10.1016/S1995-7645(12)60129-1

Source DB:  PubMed          Journal:  Asian Pac J Trop Med        ISSN: 1995-7645            Impact factor:   1.226


  6 in total

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