Literature DB >> 22838253

Role of thoracotomy and metastatectomy in gestational trophoblastic neoplasia: a single center experience.

Constantine Alifrangis1, Michelle J Wilkinson, Demetrios C Stefanou, Jagdeep S Virk, Jon Anderson, Michael J Seckl.   

Abstract

Gestational trophoblastic neoplasia (GTN) is a rare collection of malignancies which are usually curable with modern chemotherapy. Lung metastasis is a relatively common feature of these malignancies and is not considered an adverse prognostic feature. Occasionally, however, the management of these patients necessitates adjuvant thoracic surgery, either to establish the diagnosis or to potentially provide a curative resection of drug-resistant foci of disease. This case series highlights 5 such cases in which thoracic surgery has significantly contributed to the management and outcome of complicated GTN patients, and suggests when thoracic surgery should be considered in this rare group of patients.

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Year:  2012        PMID: 22838253

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  2 in total

Review 1.  Management of Chemoresistant and Quiescent Gestational Trophoblastic Disease.

Authors:  Siew-Fei Ngu; Karen K L Chan
Journal:  Curr Obstet Gynecol Rep       Date:  2014-01-04

2.  High-risk gestational choriocarcinoma with an unusual presentation and the treatment course of refractory or quiescent/minimally invasive disease.

Authors:  Yutaka Nagai; Tomoko Nakamoto; Tadaharu Nakasone; Yusuke Taira; Yoichi Aoki
Journal:  Gynecol Oncol Rep       Date:  2018-10-03
  2 in total

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