Literature DB >> 22837928

Virilizing adrenocortical carcinoma in a child: A rare enigma.

Varuna Sipayya1, Yogesh K Yadav, Rashmi Arora, Uma Sharma, Kusum Gupta.   

Abstract

Adrenocortical carcinomas are rare tumors with an incidence of one to two cases per million population and are still more rarer in the pediatric age group. Adrenocortical carcinomas can be functional or may be unassociated with syndromes of hormone overproduction. It is very important to differentiate an adrenocortical adenoma from a carcinoma, as both share a large number of phenotypic features, and assess their prognosis, as adrenocortical carcinoma may need an adjuvant therapy. In this communication, we describe the case of a two-year-old boy, who presented with iso-sexual precocious puberty, having features of virilization, which included growth of facial and pubic hair, deepening of voice, and penile growth.

Entities:  

Keywords:  Adrenocortical tumor; Weiss criteria; virilization

Year:  2012        PMID: 22837928      PMCID: PMC3401768          DOI: 10.4103/2230-8210.98025

Source DB:  PubMed          Journal:  Indian J Endocrinol Metab        ISSN: 2230-9500


  4 in total

1.  Virilising adrenocortical carcinoma.

Authors:  Dilip Kumar Pal; Anup Kumar Kundu; Subrata Chakrabortty; Shikha Das
Journal:  J Indian Med Assoc       Date:  2002-04

Review 2.  Adrenocortical tumors in children.

Authors:  R C Ribeiro; E L Michalkiewicz; B C Figueiredo; L DeLacerda; F Sandrini; M D Pianovsky; G Sampaio; R Sandrini
Journal:  Braz J Med Biol Res       Date:  2000-10       Impact factor: 2.590

3.  Weiss criteria in large adrenocortical tumors: a validation study.

Authors:  Manoj Jain; Shalini Kapoor; Anand Mishra; Sushil Gupta; Amit Agarwal
Journal:  Indian J Pathol Microbiol       Date:  2010 Apr-Jun       Impact factor: 0.740

4.  Adrenal cortical carcinoma. Epidemiology and treatment with mitotane and a review of the literature.

Authors:  M D Wooten; D K King
Journal:  Cancer       Date:  1993-12-01       Impact factor: 6.860

  4 in total
  1 in total

Review 1.  Adrenocortical carcinoma: Pediatric aspects (Review).

Authors:  Florica Sandru; Răzvan-Cosmin Petca; Mara Carsote; Aida Petca; Mihai Cristian Dumitrascu; Adina Ghemigian
Journal:  Exp Ther Med       Date:  2022-02-16       Impact factor: 2.447

  1 in total

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